Literature DB >> 10420530

[Rectal carcinoma. Optimizing therapy by partial or total mesorectum removal].

C A Maurer1, P Renzulli, J D Meyer, M W Büchler.   

Abstract

The role of total mesorectal excision for rectal cancer treatment is one of the most exciting findings in surgical oncology of the recent years. The patient's prognosis largely depends on the surgical quality of rectal resection. The excision of the cancer bearing rectum has to follow very precisely along the mesorectal fascia by sharp dissection without damaging the mesorectum itself. This technique reduces the local recurrence rate to below 10% and allows long-term survival in two thirds of all patients. Rectal cancers of the middle and lower third of the rectum need to be treated by total mesorectal excision down to the muscular pelvic floor, the ones of the upper third and the sigmoideo-rectal junction are appropriately treated by partial mesorectal excision down to 5 cm below the tumor. No additional survival benefit may be expected when pelvic lymphadenectomy has been performed. The direct tumor spread along the bowel wall and the lymphatic tumor spread in a caudal direction are uncommon and late findings in rectal cancer disease. Low and ultralow rectal carcinomas may therefore be treated by a sphincter preserving procedure respecting a safety margin of at least 1 to 2 cm. Thus, continence preserving surgery may be performed in over 80% of patients suffering from rectal cancer without compromising long-term outcome.

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Mesh:

Year:  1999        PMID: 10420530

Source DB:  PubMed          Journal:  Zentralbl Chir        ISSN: 0044-409X            Impact factor:   0.942


  5 in total

Review 1.  Required distal mesorectal resection margin in partial mesorectal excision: a systematic review on distal mesorectal spread.

Authors:  A A J Grüter; A S van Lieshout; S E van Oostendorp; J C F Ket; M Tenhagen; F C den Boer; R Hompes; P J Tanis; J B Tuynman
Journal:  Tech Coloproctol       Date:  2022-08-29       Impact factor: 3.699

2.  The pathological assessment of mesorectal excision: implications for further treatment and quality management.

Authors:  P Hermanek; P Hermanek; W Hohenberger; M Klimpfinger; F Köckerling; T Papadopoulos
Journal:  Int J Colorectal Dis       Date:  2003-02-14       Impact factor: 2.571

3.  Prospective multicenter registration study of colorectal cancer: significant variations in radicality and oncosurgical quality-Swiss Group for Clinical Cancer Research Protocol SAKK 40/00.

Authors:  Christoph A Maurer; Daniel Dietrich; Martin K Schilling; Urs Metzger; Urban Laffer; Peter Buchmann; Bruno Lerf; Peter Villiger; Gian Melcher; Christian Klaiber; Christian Bilat; Peter Brauchli; Luigi Terracciano; Katharina Kessler
Journal:  Int J Colorectal Dis       Date:  2016-10-07       Impact factor: 2.571

4.  Factors Influencing Oncologic Outcomes after Tumor-specific Mesorectal Excision for Rectal Cancer.

Authors:  Kil Yeon Lee
Journal:  J Korean Soc Coloproctol       Date:  2012-04-30

Review 5.  Introduction to Total Mesorectal Excision.

Authors:  Samir Delibegovic
Journal:  Med Arch       Date:  2017-12
  5 in total

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