Literature DB >> 10419855

Positron emission tomography neuroreceptor imaging as a tool in drug discovery, research and development.

H D Burns1, T G Hamill, W S Eng, B Francis, C Fioravanti, R E Gibson.   

Abstract

Improved communication and cooperation between research-driven drug companies and academic positron emission tomography (PET) centers, coupled with improvements in PET camera resolution, the availability of small animal PET cameras and a growing list of neuroreceptor-specific PET tracers, have all contributed to a substantial increase in the use and value of PET as a tool in central nervous system drug discovery and development.

Mesh:

Year:  1999        PMID: 10419855     DOI: 10.1016/S1367-5931(99)80059-3

Source DB:  PubMed          Journal:  Curr Opin Chem Biol        ISSN: 1367-5931            Impact factor:   8.822


  5 in total

1.  Rapid and Efficient Radiosyntheses of Meta-substituted [F]Fluoroarenes from [F]Fluoride Ion and Diaryliodonium Tosylates within a Microreactor.

Authors:  Joong-Hyun Chun; Shuiyu Lu; Victor W Pike
Journal:  European J Org Chem       Date:  2011-08

2.  Efficient (18)F-labeling of large 37-amino-acid pHLIP peptide analogues and their biological evaluation.

Authors:  Pierre Daumar; Cindy A Wanger-Baumann; NagaVaraKishore Pillarsetty; Laura Fabrizio; Sean D Carlin; Oleg A Andreev; Yana K Reshetnyak; Jason S Lewis
Journal:  Bioconjug Chem       Date:  2012-07-30       Impact factor: 4.774

3.  Syntheses of 11C- and 18F-labeled carboxylic esters within a hydrodynamically-driven micro-reactor.

Authors:  Shui-Yu Lu; Paul Watts; Frederick T Chin; Jinsoo Hong; John L Musachio; Emmanuelle Briard; Victor W Pike
Journal:  Lab Chip       Date:  2004-09-28       Impact factor: 6.799

4.  Nucleophile assisting leaving groups: a strategy for aliphatic 18F-fluorination.

Authors:  Shuiyu Lu; Salvatore D Lepore; Song Ye Li; Deboprosad Mondal; Pamela C Cohn; Anjan K Bhunia; Victor W Pike
Journal:  J Org Chem       Date:  2009-08-07       Impact factor: 4.354

5.  In vivo imaging of pyrrole-imidazole polyamides with positron emission tomography.

Authors:  Daniel A Harki; Nagichettiar Satyamurthy; David B Stout; Michael E Phelps; Peter B Dervan
Journal:  Proc Natl Acad Sci U S A       Date:  2008-08-27       Impact factor: 11.205

  5 in total

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