Literature DB >> 10419841

Apoptosis: a potential target for discovering novel therapies for cardiovascular diseases.

T L Yue1, E H Ohlstein, R R Ruffolo.   

Abstract

The realization that apoptosis is genetically programmed raises the exciting prospect that modulating apoptosis may provide novel approaches for treatment of cardiovascular diseases in which apoptosis has been demonstrated. Low molecular weight inhibitors of caspases and mitogen-activated protein kinases have been evaluated, with promising results in a variety of cardiovascular apoptotic models.

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Year:  1999        PMID: 10419841     DOI: 10.1016/S1367-5931(99)80069-6

Source DB:  PubMed          Journal:  Curr Opin Chem Biol        ISSN: 1367-5931            Impact factor:   8.822


  6 in total

Review 1.  Apoptosis-detecting radioligands: current state of the art and future perspectives.

Authors:  Christophe M M Lahorte; Jean-Luc Vanderheyden; Neil Steinmetz; Christophe Van de Wiele; Rudi A Dierckx; Guido Slegers
Journal:  Eur J Nucl Med Mol Imaging       Date:  2004-05-12       Impact factor: 9.236

2.  Inflammatory cytokines, apoptotic, tissue injury and remodeling biomarkers in children with congenital heart disease.

Authors:  Yasser E Nassef; Manal A Hamed; Hanan F Aly
Journal:  Indian J Clin Biochem       Date:  2013-05-23

Review 3.  Classification of scaffold-hopping approaches.

Authors:  Hongmao Sun; Gregory Tawa; Anders Wallqvist
Journal:  Drug Discov Today       Date:  2011-10-26       Impact factor: 7.851

4.  Role of proteases in the pathophysiology of cardiac disease.

Authors:  Raja B Singh; Sucheta P Dandekar; Vijayan Elimban; Suresh K Gupta; Naranjan S Dhalla
Journal:  Mol Cell Biochem       Date:  2004-08       Impact factor: 3.396

5.  Anti-Proliferative Effect of Triterpenoidal Glycosides from the Roots of Anemone vitifolia through a Pro-Apoptotic Way.

Authors:  Changcai Bai; Yunyun Ye; Xiao Feng; Ruifeng Bai; Lu Han; Xiuping Zhou; Xinyao Yang; Pengfei Tu; Xingyun Chai
Journal:  Molecules       Date:  2017-04-17       Impact factor: 4.411

6.  Capsaicin induces apoptosis in MG63 human osteosarcoma cells via the caspase cascade and the antioxidant enzyme system.

Authors:  Won Ho Cho; Hyun Joo Lee; Yoon Ji Choi; Joo Han Oh; Han Soo Kim; Hwan Seong Cho
Journal:  Mol Med Rep       Date:  2013-10-17       Impact factor: 2.952

  6 in total

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