| Literature DB >> 10418152 |
A Matĕjcková-Forejtová1, O Kinclová, H Sychrová.
Abstract
The Candida albicans amino-acid Can1 permease expressed in Saccharomyces cerevisiae is degraded in the vacuole after internalisation by endocytosis. The CaCan1 inactivation and degradation is slow and not inducible by ammonium ions or 'stress' conditions. Using Saccharomyces cerevisiae mutants defective in ubiquitin-protein ligase and ubiquitin-protein hydrolase we have shown that the degradation of heterologous CaCan1 permease is ubiquitin dependent.Entities:
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Year: 1999 PMID： 10418152 DOI： 10.1111/j.1574-6968.1999.tb13670.x
Source DB: PubMed Journal: FEMS Microbiol Lett ISSN： 0378-1097 Impact factor: 2.742