Literature DB >> 10417082

Heterogeneity of coronary heart disease risk factors in Indian, Pakistani, Bangladeshi, and European origin populations: cross sectional study.

R Bhopal1, N Unwin, M White, J Yallop, L Walker, K G Alberti, J Harland, S Patel, N Ahmad, C Turner, B Watson, D Kaur, A Kulkarni, M Laker, A Tavridou.   

Abstract

OBJECTIVE: To compare coronary risk factors and disease prevalence among Indians, Pakistanis, and Bangladeshis, and in all South Asians (these three groups together) with Europeans.
DESIGN: Cross sectional survey.
SETTING: Newcastle upon Tyne. PARTICIPANTS: 259 Indian, 305 Pakistani, 120 Bangladeshi, and 825 European men and women aged 25-74 years. MAIN OUTCOME MEASURES: Social and economic circumstances, lifestyle, self reported symptoms and diseases, blood pressure, electrocardiogram, and anthropometric, haematological, and biochemical measurements.
RESULTS: There were differences in social and economic circumstances, lifestyles, anthropometric measures and disease both between Indians, Pakistanis, and Bangladeshis and between all South Asians and Europeans. Bangladeshis and Pakistanis were the poorest groups. For most risk factors, the Bangladeshis (particularly men) fared the worst: smoking was most common (57%) in that group, and Bangladeshis had the highest concentrations of triglycerides (2.04 mmol/l) and fasting blood glucose (6.6 mmol/l) and the lowest concentration of high density lipoprotein cholesterol (0.97 mmol/l). Blood pressure, however, was lowest in Bangladeshis. Bangladeshis were the shortest (men 164 cm tall v 170 cm for Indians and 174 cm for Europeans). A higher proportion of Pakistani and Bangladeshi men had diabetes (22.4% and 26.6% respectively) than Indians (15.2%). Comparisons of all South Asians with Europeans hid some important differences, but South Asians were still disadvantaged in a wide range of risk factors. Findings in women were similar.
CONCLUSION: Risk of coronary heart disease is not uniform among South Asians, and there are important differences between Indians, Pakistanis, and Bangladeshis for many coronary risk factors. The belief that, except for insulin resistance, South Asians have lower levels of coronary risk factors than Europeans is incorrect, and may have arisen from combining ethnic subgroups and examining a narrow range of factors.

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Mesh:

Year:  1999        PMID: 10417082      PMCID: PMC28170          DOI: 10.1136/bmj.319.7204.215

Source DB:  PubMed          Journal:  BMJ        ISSN: 0959-8138


  17 in total

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Authors:  M A Mendall
Journal:  BMJ       Date:  1998-03-28

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Authors:  A J Coldman; T Braun; R P Gallagher
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Authors:  N Shaukat; D P de Bono
Journal:  Postgrad Med J       Date:  1994-05       Impact factor: 2.401

6.  Diet and risk factors for coronary heart disease in Asians in northwest London.

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Journal:  Lancet       Date:  1985-11-16       Impact factor: 79.321

7.  Coronary risk in a British Punjabi population: comparative profile of non-biochemical factors.

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Journal:  Int J Epidemiol       Date:  1994-02       Impact factor: 7.196

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Journal:  World Health Stat Q       Date:  1988

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Authors:  P M McKeigue; B Shah; M G Marmot
Journal:  Lancet       Date:  1991-02-16       Impact factor: 79.321

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Authors:  P M McKeigue; G J Miller; M G Marmot
Journal:  J Clin Epidemiol       Date:  1989       Impact factor: 6.437

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  152 in total

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Authors:  G D Smith
Journal:  Am J Public Health       Date:  2000-11       Impact factor: 9.308

2.  Revisiting race/ethnicity as a variable in health research.

Authors:  Raj Bhopal
Journal:  Am J Public Health       Date:  2002-02       Impact factor: 9.308

3.  Epidemic of cardiovascular disease in South Asians.

Authors:  Raj Bhopal
Journal:  BMJ       Date:  2002-03-16

4.  Anaemia in Chinese, South Asian, and European populations in Newcastle upon Tyne: cross sectional study.

Authors:  C Fischbacher; R Bhopal; S Patel; M White; N Unwin; K G Alberti
Journal:  BMJ       Date:  2001-04-21

5.  Heterogeneity among Indians, Pakistanis, and Bangladeshis is key to racial inequities.

Authors:  Raj S Bhopal
Journal:  BMJ       Date:  2002-10-19

6.  Screening for diabetes using an oral glucose tolerance test within a western multi-ethnic population identifies modifiable cardiovascular risk: the ADDITION-Leicester study.

Authors:  D R Webb; L J Gray; K Khunti; B Srinivasan; N Taub; S Campbell; J Barnett; A Farooqi; J B Echouffo-Tcheugui; S J Griffin; N J Wareham; M J Davies
Journal:  Diabetologia       Date:  2011-06-03       Impact factor: 10.122

7.  Preventing diabetes in south Asians.

Authors:  Tahseen A Chowdhury; Clare Grace; Peter G Kopelman
Journal:  BMJ       Date:  2003-11-08

8.  Prescribing of lipid lowering drugs to South Asian patients: ecological study.

Authors:  Mahendra G Patel; David J Wright; Paramjit S Gill; David Jerwood; Jonathan Silcock; Henry Chrystyn
Journal:  BMJ       Date:  2002-07-06

9.  Many South Asian people probably need pre-diabetes care.

Authors:  R Bhopal; C M Fischbacher
Journal:  BMJ       Date:  2002-10-26

10.  Glossary of terms relating to ethnicity and race: for reflection and debate.

Authors:  R Bhopal
Journal:  J Epidemiol Community Health       Date:  2004-06       Impact factor: 3.710

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