Literature DB >> 10416385

A monoclonal antibody that recognizes the predicted tick-borne encephalitis virus E protein fusion sequence blocks fusion.

T D Volkova1, M F Vorovitch, V T Ivanov, A V Timofeev, O M Volpina.   

Abstract

The fusion motif of tick-borne encephalitis virus E protein has been predicted to be located within its conserved region (98-120). Results are presented to demonstrate that non-neutralizing monoclonal antibody which recognizes a synthetic peptide corresponding to residues 98-113 of the E protein sequence can block the fusion of the virus particles with artificial membranes.

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Year:  1999        PMID: 10416385     DOI: 10.1007/s007050050566

Source DB:  PubMed          Journal:  Arch Virol        ISSN: 0304-8608            Impact factor:   2.574


  3 in total

1.  Mutational evidence for an internal fusion peptide in flavivirus envelope protein E.

Authors:  S L Allison; J Schalich; K Stiasny; C W Mandl; F X Heinz
Journal:  J Virol       Date:  2001-05       Impact factor: 5.103

2.  A broadly flavivirus cross-neutralizing monoclonal antibody that recognizes a novel epitope within the fusion loop of E protein.

Authors:  Yong-Qiang Deng; Jian-Xin Dai; Guang-Hui Ji; Tao Jiang; Hua-Jing Wang; Hai-ou Yang; Weng-Long Tan; Ran Liu; Man Yu; Bao-Xue Ge; Qing-Yu Zhu; E-De Qin; Ya-Jun Guo; Cheng-Feng Qin
Journal:  PLoS One       Date:  2011-01-11       Impact factor: 3.240

Review 3.  Structures and mechanisms in flavivirus fusion.

Authors:  F X Heinz; S L Allison
Journal:  Adv Virus Res       Date:  2000       Impact factor: 9.937

  3 in total

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