| Literature DB >> 10416205 |
R A Gomez1, M L Sequeira Lopez, L Fernandez, D R Cherñavvsky, V F Norwood.
Abstract
Kidney morphogenesis is accomplished by the coordinated interaction of molecular signals that culminate in the production of an organ that is architecturally and functionally ready for extrauterine, free life. In humans, nephrogenesis is completed before birth. However the kidney continues to mature both from a functional and anatomical point of view. Throughout its development, the kidney is susceptible to a variety of injurious agents. This brief review considers the basic mechanisms of kidney organogenesis and functional maturation. To illustrate some concepts, the renal alterations caused by interference with a normal regulatory system, the renin-angiotensin system is discussed.Entities:
Mesh:
Year: 1999 PMID: 10416205 DOI: 10.3109/08860229909085090
Source DB: PubMed Journal: Ren Fail ISSN: 0886-022X Impact factor: 2.606