Literature DB >> 10416054

CoQ10: could it have a role in cancer management?

S Hodges1, N Hertz, K Lockwood, R Lister.   

Abstract

Coenzyme Q10 or ubiquinone has been shown to have both anti-cancer and immune system enhancing properties when tested in animals. Preliminary results reported here suggest that it might inhibit tumour-associated cytokines. Clinical studies conducted with combination therapies of CoQ10 and other antioxidants are ongoing, but the results are difficult evaluate owing to the lack of proper control groups and of initial randomisation. Also on the basis of some anti-cancer effects of antioxidants reported in literature, further animal studies and a proper clinical trial of coenzyme Q10 in cancer patients are needed.

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Year:  1999        PMID: 10416054     DOI: 10.1002/biof.5520090237

Source DB:  PubMed          Journal:  Biofactors        ISSN: 0951-6433            Impact factor:   6.113


  4 in total

1.  Plasma coenzyme Q10 levels and postmenopausal breast cancer risk: the multiethnic cohort study.

Authors:  Weiwen Chai; Robert V Cooney; Adrian A Franke; Yurii B Shvetsov; Christian P Caberto; Lynne R Wilkens; Loïc Le Marchand; Brian E Henderson; Laurence N Kolonel; Marc T Goodman
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2010-07-28       Impact factor: 4.254

2.  Molecular mechanisms of statin intolerance.

Authors:  Anna Gluba-Brzozka; Beata Franczyk; Peter P Toth; Jacek Rysz; Maciej Banach
Journal:  Arch Med Sci       Date:  2016-05-18       Impact factor: 3.318

Review 3.  The Involvement of the Oxidative Stress Status in Cancer Pathology: A Double View on the Role of the Antioxidants.

Authors:  Kamal Fatima Zahra; Radu Lefter; Ahmad Ali; Ech-Chahad Abdellah; Constantin Trus; Alin Ciobica; Daniel Timofte
Journal:  Oxid Med Cell Longev       Date:  2021-08-05       Impact factor: 6.543

Review 4.  Coenzyme Q10 and Immune Function: An Overview.

Authors:  David Mantle; Robert A Heaton; Iain P Hargreaves
Journal:  Antioxidants (Basel)       Date:  2021-05-11
  4 in total

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