Literature DB >> 10414342

Development of a novel class of subtype-selective nicotinic receptor antagonist: pyridine-N-substituted nicotine analogs.

L P Dwoskin1, L H Wilkins, J R Pauly, P A Crooks.   

Abstract

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Year:  1999        PMID： 10414342     DOI： 10.1111/j.1749-6632.1999.tb11334.x

Source DB:  PubMed          Journal:  Ann N Y Acad Sci        ISSN： 0077-8923            Impact factor:   5.691


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  7 in total

1.  Discovery of a novel nicotinic receptor antagonist for the treatment of nicotine addiction: 1-(3-Picolinium)-12-triethylammonium-dodecane dibromide (TMPD).

Authors:  Linda P Dwoskin; B Matthew Joyce; Guangrong Zheng; Nichole M Neugebauer; Vamshi K Manda; Paul Lockman; Roger L Papke; Michael T Bardo; Peter A Crooks
Journal:  Biochem Pharmacol       Date:  2007-07-21       Impact factor: 5.858

2.  Nicotine increases dopamine transporter function in rat striatum through a trafficking-independent mechanism.

Authors:  Lisa S Middleton; Subbu Apparsundaram; Kelley A King-Pospisil; Linda P Dwoskin
Journal:  Eur J Pharmacol       Date:  2006-10-19       Impact factor: 4.432

Review 3.  Nicotinic receptor antagonists as treatments for nicotine abuse.

Authors:  Peter A Crooks; Michael T Bardo; Linda P Dwoskin
Journal:  Adv Pharmacol       Date:  2014

4.  Novel bis-, tris-, and tetrakis-tertiary amino analogs as antagonists at neuronal nicotinic receptors that mediate nicotine-evoked dopamine release.

Authors:  Zhenfa Zhang; Guangrong Zheng; Marharyta Pivavarchyk; A Gabriela Deaciuc; Linda P Dwoskin; Peter A Crooks
Journal:  Bioorg Med Chem Lett       Date:  2010-11-24       Impact factor: 2.823

5.  Discovery of non-peptide, small molecule antagonists of α9α10 nicotinic acetylcholine receptors as novel analgesics for the treatment of neuropathic and tonic inflammatory pain.

Authors:  Guangrong Zheng; Zhenfa Zhang; Cheryl Dowell; Elzbieta Wala; Linda P Dwoskin; Joseph R Holtman; J Michael McIntosh; Peter A Crooks
Journal:  Bioorg Med Chem Lett       Date:  2011-02-23       Impact factor: 2.823

6.  Tetrakis-azaaromatic quaternary ammonium salts: novel subtype-selective antagonists at neuronal nicotinic receptors that mediate nicotine-evoked dopamine release.

Authors:  Zhenfa Zhang; Guangrong Zheng; Marharyta Pivavarchyk; A Gabriela Deaciuc; Linda P Dwoskin; Peter A Crooks
Journal:  Bioorg Med Chem Lett       Date:  2008-09-26       Impact factor: 2.823

7.  QSAR study on maximal inhibition (Imax) of quaternary ammonium antagonists for S-(-)-nicotine-evoked dopamine release from dopaminergic nerve terminals in rat striatum.

Authors:  Fang Zheng; Matthew J McConnell; Chang-Guo Zhan; Linda P Dwoskin; Peter A Crooks
Journal:  Bioorg Med Chem       Date:  2009-05-08       Impact factor: 3.641
  7 in total

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