Literature DB >> 10414

Structure of aluminum hydroxide gel II: aging mechanism.

S L Nail, J L White, S L Hem.   

Abstract

The aging of aluminum hydroxide gel prepared by the reaction of aluminum chloride and ammonium hydroxide was studied by measurement of pH, acid-consuming capacity, hydroxide to aluminum ratio, chloride activity, and X-ray line broadening. The results were consistent with a polymer model involving particle growth by a deprotonation-dehydration mechanism. Anions inhibit this reaction by binding to the positively charged edges of the hydroxyaluminum polymers.

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Year:  1976        PMID: 10414     DOI: 10.1002/jps.2600650815

Source DB:  PubMed          Journal:  J Pharm Sci        ISSN: 0022-3549            Impact factor:   3.534


  3 in total

1.  Characterization of the MN gp120 HIV-1 vaccine: antigen binding to alum.

Authors:  R P Weissburg; P W Berman; J L Cleland; D Eastman; F Farina; S Frie; A Lim; J Mordenti; T T Nguyen; M R Peterson
Journal:  Pharm Res       Date:  1995-10       Impact factor: 4.200

2.  Mode of action of immunological adjuvants: some physicochemical factors influencing the effectivity of polyacrylic adjuvants.

Authors:  J Kreuter; I Haenzel
Journal:  Infect Immun       Date:  1978-02       Impact factor: 3.441

3.  Aluminum compounds used as adjuvants in vaccines.

Authors:  S Shirodkar; R L Hutchinson; D L Perry; J L White; S L Hem
Journal:  Pharm Res       Date:  1990-12       Impact factor: 4.200

  3 in total

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