Literature DB >> 10408309

Evaluation of serum arginase activity in benign prostatic hypertrophy and prostatic cancer.

S Elgün1, A Keskineğe, E Yilmaz, S Baltaci, Y Bedük.   

Abstract

Activities of arginase, prostatic acid phosphatase (PAP) and prostate specific antigen (PSA) were determined in sera of healthy male controls, benign prostatic hypertrophy (BPH) and prostatic cancer patients. Serum arginase activity in the cancer group (22.8+/-11.6 U/l) was significantly lower than in both the control (33.64+/-16.19 U/l) and the BPH group (58.8+/-11.6 U/l) (p<0.001, respectively), while the BPH group had significantly higher levels compared to the controls (p<0.05). However, serum arginase levels in all groups had no statistically significant correlation with PAP and PSA. Serum arginase activity correlated inversely with the Gleason grades. These results suggest that serum arginase assay may be used for the pretreatment evaluation of patients with prostatic diseases.

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Year:  1999        PMID： 10408309     DOI： 10.1023/a:1007132109061

Source DB:  PubMed          Journal:  Int Urol Nephrol        ISSN： 0301-1623            Impact factor:   2.370


  12 in total

1.  Enzymatic activities in extracts of small (20 +/- 5 mg) samples of prostatic carcinoma.

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Journal:  Anal Biochem       Date:  1990-01       Impact factor: 3.365

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Authors:  D F Gleason; G T Mellinger
Journal:  J Urol       Date:  1974-01       Impact factor: 7.450

Review 4.  Mechanisms and regulation of polyamine and putrescine biosynthesis in male genital glands and other tissues of mammals.

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Journal:  Adv Enzyme Regul       Date:  1969

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Authors:  D F Gleason
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Authors:  B Mellerup
Journal:  Clin Chem       Date:  1967-10       Impact factor: 8.327

7.  Study of activities of arginase, hexosaminidase, and leucine aminopeptidase in prostate fluid.

Authors:  A Z Vafa; P K Grover; T G Pretlow; M I Resnick
Journal:  Urology       Date:  1993-08       Impact factor: 2.649

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Authors:  T G Pretlow; B E Harris; E L Bradley; A J Bueschen; K L Lloyd; T P Pretlow
Journal:  Cancer Res       Date:  1985-01       Impact factor: 12.701

9.  Arginase activity in prostatic tissue of patients with benign prostatic hyperplasia and prostatic carcinoma.

Authors:  B E Harris; T P Pretlow; E L Bradley; G B Whitehurst; T G Pretlow
Journal:  Cancer Res       Date:  1983-06       Impact factor: 12.701

Review 10.  Putative preneoplastic foci in the human prostate.

Authors:  T G Pretlow; M Nagabhushan; M Sy; Y Guo; T P Pretlow
Journal:  J Cell Biochem Suppl       Date:  1994
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  2 in total

Review 1.  Myeloid Cell-Derived Arginase in Cancer Immune Response.

Authors:  Tomasz M Grzywa; Anna Sosnowska; Paweł Matryba; Zuzanna Rydzynska; Marcin Jasinski; Dominika Nowis; Jakub Golab
Journal:  Front Immunol       Date:  2020-05-15       Impact factor: 7.561

Review 2.  Arginine and Arginases Modulate Metabolism, Tumor Microenvironment and Prostate Cancer Progression.

Authors:  Andreia Matos; Marcos Carvalho; Manuel Bicho; Ricardo Ribeiro
Journal:  Nutrients       Date:  2021-12-16       Impact factor: 5.717
  2 in total

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