Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Tandem mass spectrometry--the potential.

Literature DB >> 10407788

Tandem mass spectrometry--the potential.

Abstract

We summarize the current status of the use of tandem mass spectrometry for the detection of inherited metabolic disorders and the investigation of the pathophysiology of these conditions. We also indicate some of the more recent developments of this technology that have potential diagnostic applications.

Entities: Disease

Mesh：

Year: 1999 PMID： 10407788 DOI： 10.1023/a:1005520726774

Source DB: PubMed Journal: J Inherit Metab Dis ISSN： 0141-8955 Impact factor: 4.982

12 in total

1. Prenatal diagnosis of mitochondrial fatty acid oxidation defects.

Authors: M A Nada; C Vianey-Saban; C R Roe; J H Ding; M Mathieu; R S Wappner; M G Bialer; J A McGlynn; G Mandon
Journal: Prenat Diagn Date: 1996-02 Impact factor: 3.050

2. Intact protein electrospray ionization tandem mass spectrometry can be the sole technique used for confirming the structure of a variant hemoglobin.

Authors: H E Witkowska; B N Green; M Morris; C H Shackleton
Journal: Rapid Commun Mass Spectrom Date: 1995 Impact factor: 2.419

3. Phytanic acid and pristanic acid are oxidized by sequential peroxisomal and mitochondrial reactions in cultured fibroblasts.

Authors: N M Verhoeven; D S Roe; R M Kok; R J Wanders; C Jakobs; C R Roe
Journal: J Lipid Res Date: 1998-01 Impact factor: 5.922

4. Rapid diagnosis of phenylketonuria by quantitative analysis for phenylalanine and tyrosine in neonatal blood spots by tandem mass spectrometry.

Authors: D H Chace; D S Millington; N Terada; S G Kahler; C R Roe; L F Hofman
Journal: Clin Chem Date: 1993-01 Impact factor: 8.327

5. Rapid diagnosis of homocystinuria and other hypermethioninemias from newborns' blood spots by tandem mass spectrometry.

Authors: D H Chace; S L Hillman; D S Millington; S G Kahler; B W Adam; H L Levy
Journal: Clin Chem Date: 1996-03 Impact factor: 8.327

6. Quantitative analysis of biological membrane lipids at the low picomole level by nano-electrospray ionization tandem mass spectrometry.

Authors: B Brügger; G Erben; R Sandhoff; F T Wieland; W D Lehmann
Journal: Proc Natl Acad Sci U S A Date: 1997-03-18 Impact factor: 11.205

7. Prenatal diagnosis of organic acidemias based on amniotic fluid levels of acylcarnitines.

Authors: Y Shigematsu; I Hata; A Nakai; Y Kikawa; M Sudo; Y Tanaka; S Yamaguchi; C Jakobs
Journal: Pediatr Res Date: 1996-04 Impact factor: 3.756

8. Characterization of the testis and epididymis in mouse models of human Tay Sachs and Sandhoff diseases and partial determination of accumulated gangliosides.

Authors: J Trasler; F Saberi; I H Somani; H I Adamali; J Q Huang; S R Fortunato; G Ritter; M Gu; R Aebersold; R A Gravel; L Hermo
Journal: Endocrinology Date: 1998-07 Impact factor: 4.736