| Literature DB >> 10406649 |
M J Tozer1, E A Harper, S B Kalindjian, M J Pether, N P Shankley, G F Watt.
Abstract
Histamine was converted to a selective histamine H3-receptor antagonist by capping the primary amine with 2-naphthalenesulfonyl chloride. Higher receptor affinity and lower variability in the data from the various bioassays were achieved with the 2-naphthalensulfonamides of histamine homologues.Entities:
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Year: 1999 PMID： 10406649 DOI： 10.1016/s0960-894x(99)00272-3
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823