| Literature DB >> 10406648 |
L Strekowski1, O Zegrocka, M Henary, M Say, M J Mokrosz, B M Kotecka, L Manzel, D E Macfarlane.
Abstract
On the basis of a systematic SAR analysis of substituted quinolines, a derivative 32 was synthesized that shows half-maximal inhibition of the immunostimulatory effect of CpG-oligodeoxynucleotides in vitro at the concentration of 0.24 nM.Entities:
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Year: 1999 PMID： 10406648 DOI： 10.1016/s0960-894x(99)00291-7
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823