Literature DB >> 10405507

Psychopathology and achievement in children at high risk for developing alcoholism.

S Y Hill1, J Locke, L Lowers, J Connolly.   

Abstract

OBJECTIVE: To compare rates of psychopathology and academic achievement in children who were either at high or low risk for developing alcoholism and to determine whether academic deficits would predict prospectively the presence of psychopathology occurring within the next year.
METHOD: Children and adolescents, aged 8 to 18 years, were evaluated as part of a longitudinal follow-up. Diagnoses obtained by using the Schedule for Affective Disorders and Schizophrenia for School-Age Children and grade-equivalent scores from the reading, spelling, and arithmetic sections of the Wide Range Achievement Test were determined at yearly intervals.
RESULTS: High-risk offspring were more likely to have a diagnosable disorder. In addition, analyses using the mother's and father's diagnosis of alcoholism as a covariate showed higher hazard ratios for selected disorders (depression, affective disorder, attention-deficit/hyperactivity disorder, and conduct disorder), some of which were gender-dependent. Logistic regression analysis of achievement test scores demonstrated that reading and math scores predicted the presence of childhood psychopathology at the following annual evaluation.
CONCLUSIONS: Children from pedigrees with a high density of alcoholism are at greater risk for developing psychopathology. Furthermore, observed deficits in academic performance may be considered an indicator of a developing diagnosable illness.

Entities:  

Mesh:

Year:  1999        PMID: 10405507     DOI: 10.1097/00004583-199907000-00019

Source DB:  PubMed          Journal:  J Am Acad Child Adolesc Psychiatry        ISSN: 0890-8567            Impact factor:   8.829


  15 in total

1.  Maternal smoking and drinking during pregnancy and the risk for child and adolescent psychiatric disorders.

Authors:  S Y Hill; L Lowers; J Locke-Wellman; S A Shen
Journal:  J Stud Alcohol       Date:  2000-09

2.  Caudate Volume in Offspring at Ultra High Risk for Alcohol Dependence: COMT Val158Met, DRD2, Externalizing Disorders, and Working Memory.

Authors:  Shirley Y Hill; Sarah Lichenstein; Shuhui Wang; Howard Carter; Michael McDermott
Journal:  Adv J Mol Imaging       Date:  2013-10-01

3.  Meta-Analyses of Externalizing Disorders: Genetics or Prenatal Alcohol Exposure?

Authors:  Leah Wetherill; Tatiana Foroud; Charles Goodlett
Journal:  Alcohol Clin Exp Res       Date:  2017-11-27       Impact factor: 3.455

Review 4.  Neural plasticity, human genetics, and risk for alcohol dependence.

Authors:  Shirley Y Hill
Journal:  Int Rev Neurobiol       Date:  2010       Impact factor: 3.230

5.  Disruption of orbitofrontal cortex laterality in offspring from multiplex alcohol dependence families.

Authors:  Shirley Y Hill; Shuhui Wang; Bryan Kostelnik; Howard Carter; Brian Holmes; Michael McDermott; Nicholas Zezza; Scott Stiffler; Matcheri S Keshavan
Journal:  Biol Psychiatry       Date:  2008-11-04       Impact factor: 13.382

6.  Cerebellar volume in offspring from multiplex alcohol dependence families.

Authors:  Shirley Y Hill; Srirangam Muddasani; Konasale Prasad; Jeffrey Nutche; Stuart R Steinhauer; Joelle Scanlon; Michael McDermott; Matcheri Keshavan
Journal:  Biol Psychiatry       Date:  2006-03-14       Impact factor: 13.382

7.  Severity of alcoholism in Indian males: Correlation with age of onset and family history of alcoholism.

Authors:  Pradeep R Johnson; Saira Banu; M V Ashok
Journal:  Indian J Psychiatry       Date:  2010-07       Impact factor: 1.759

8.  Psychopathology among offspring of parents with schizophrenia: relationship to premorbid impairments.

Authors:  Matcheri Keshavan; Debra M Montrose; Rajaprabhakaran Rajarethinam; Vaibhav Diwadkar; Konasale Prasad; John A Sweeney
Journal:  Schizophr Res       Date:  2008-04-28       Impact factor: 4.939

9.  Psychopathology in offspring from multiplex alcohol dependence families with and without parental alcohol dependence: a prospective study during childhood and adolescence.

Authors:  Shirley Y Hill; Sa Shen; Lisa Lowers; Jeannette Locke-Wellman; Abigail G Matthews; Michael McDermott
Journal:  Psychiatry Res       Date:  2008-07-01       Impact factor: 3.222

10.  Childhood risk factors for young adult substance dependence outcome in offspring from multiplex alcohol dependence families: a prospective study.

Authors:  Shirley Y Hill; Stuart R Steinhauer; Jeannette Locke-Wellman; Richard Ulrich
Journal:  Biol Psychiatry       Date:  2009-07-29       Impact factor: 13.382

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