Literature DB >> 10404540

Mechanism of antiviral activity of triterpenoid saponins.

C M Simões1, M Amoros, L Girre.   

Abstract

Triterpenoid saponins are naturally occurring sugar conjugates of triterpenes possessing various biological activities, including antiviral action. Two substances isolated from natural sources were tested against herpes simplex virus type 1 replication. They did not show evidence of cytotoxicity under antiviral test conditions. The triterpenoid saponin, isolated from a Brazilian plant (s21), represents the oleanane group and inhibited herpes simplex virus type 1 DNA synthesis. The triterpenoid saponin, isolated from a Chinese plant (s17), represents the ursane group and seemed to inhibit viral capsid protein synthesis of herpes simplex virus type 1.

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Year:  1999        PMID： 10404540     DOI： 10.1002/(SICI)1099-1573(199906)13:4<323::AID-PTR448>3.0.CO;2-C

Source DB:  PubMed          Journal:  Phytother Res        ISSN： 0951-418X            Impact factor:   5.878


  18 in total

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Journal:  Biomed Rep       Date:  2016-10-25

2.  Samarangenin B from Limonium sinense suppresses herpes simplex virus type 1 replication in Vero cells by regulation of viral macromolecular synthesis.

Authors:  Yuh-Chi Kuo; Lie-Chwen Lin; Wei-Jern Tsai; Cheng-Jen Chou; Szu-Hao Kung; Yen-Hui Ho
Journal:  Antimicrob Agents Chemother       Date:  2002-09       Impact factor: 5.191

Review 3.  Checklist of African Soapy Saponin-Rich Plants for Possible Use in Communities' Response to Global Pandemics.

Authors:  Yvonne Kunatsa; David R Katerere
Journal:  Plants (Basel)       Date:  2021-04-22

4.  Coadministration of Hedera helix L. Extract Enabled Mice to Overcome Insufficient Protection against Influenza A/PR/8 Virus Infection under Suboptimal Treatment with Oseltamivir.

Authors:  Eun-Hye Hong; Jae-Hyoung Song; Aeri Shim; Bo-Ra Lee; Bo-Eun Kwon; Hyuk-Hwan Song; Yeon-Jeong Kim; Sun-Young Chang; Hyeon Gun Jeong; Jong Geal Kim; Sang-Uk Seo; HyunPyo Kim; YongSoo Kwon; Hyun-Jeong Ko
Journal:  PLoS One       Date:  2015-06-22       Impact factor: 3.240

Review 5.  Candidate Anti-COVID-19 Medicinal Plants from Ethiopia: A Review of Plants Traditionally Used to Treat Viral Diseases.

Authors:  Dires Tegen; Kindalem Dessie; Destaw Damtie
Journal:  Evid Based Complement Alternat Med       Date:  2021-06-04       Impact factor: 2.629

6.  In vitro inhibitory activity against HPV of the monoterpenoid zinc tetra-ascorbo-camphorate.

Authors:  Ralph Sydney Mboumba Bouassa; Bernard Gombert; Gabin Mwande-Maguene; Aurèle Mannarini; Laurent Bélec
Journal:  Heliyon       Date:  2021-06-06

7.  Therapeutic effect of total ginseng saponin on skin wound healing.

Authors:  Young Soo Kim; Ik-Hyun Cho; Moon-Jin Jeong; Soon-Jeong Jeong; Seung Yeol Nah; Young-Sik Cho; Seung Hyun Kim; Ara Go; Se Eun Kim; Seong Soo Kang; Chang Jong Moon; Jong Choon Kim; Sung Ho Kim; Chun Sik Bae
Journal:  J Ginseng Res       Date:  2011-09       Impact factor: 6.060

8.  Antiviral Activity of Hederasaponin B from Hedera helix against Enterovirus 71 Subgenotypes C3 and C4a.

Authors:  Jaehyoung Song; Sang-Gu Yeo; Eun-Hye Hong; Bo-Ra Lee; Jin-Won Kim; Jeonghoon Kim; Hyeongun Jeong; Yongsoo Kwon; Hyunpyo Kim; Sangwon Lee; Jae-Hak Park; Hyun-Jeong Ko
Journal:  Biomol Ther (Seoul)       Date:  2014-01       Impact factor: 4.634

9.  The Effect of Hydrocotyle sibthorpioides Lam. Extracts on In Vitro Dengue Replication.

Authors:  Fitrien Husin; Yean Yean Chan; Siew Hua Gan; Siti Amrah Sulaiman; Rafidah Hanim Shueb
Journal:  Evid Based Complement Alternat Med       Date:  2015-02-12       Impact factor: 2.629

10.  Evaluation of Spirulina platensis extract as natural antivirus against foot and mouth disease virus strains (A, O, SAT2).

Authors:  Hind M Daoud; Eman M Soliman
Journal:  Vet World       Date:  2015-10-31
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