Literature DB >> 10401736

Use of N-butyl-2-cyanoacrylate in elective surgical incisions--longterm outcomes.

G E Amiel1, I Sukhotnik, B Kawar, L Siplovich.   

Abstract

BACKGROUND: Histoacryl Blue (N-butyl-2-cyanoacrylate) is a tissue adhesive that has been used clinically for more than 20 years. In the last decade, N-butyl-2-cyanoacrylate has been used for cutaneous closure of low-tension lacerations in children and adults and has become a preferred method for closure of pediatric facial lacerations in many emergency rooms outside the United States. Many pediatric elective surgical procedures are performed in tension-free areas and may be suitable for closure with a tissue adhesive. In order to assess this approach, a retrospective study was conducted to evaluate the cosmetic outcomes and complications of the application of N-butyl-2-cyanoacrylate for the approximation of elective surgical incisions in a pediatric population. STUDY
DESIGN: Records of 1,098 patients, ages 1 month to 16 years, who, between January 1995 and December 1996, underwent one of the following: orchidopexy, inguinal hernia, umbilical hernia, or hydrocele repair were analyzed. In all patients, N-butyl-2-cyanoacrylate was applied to close the surgical incision. A 12-item questionnaire was created to assess the presence of complications and to determine shortterm and longterm cosmetic outcomes of the incision. Data were collected by conducting telephone interviews of family members.
RESULTS: Among the 1,033 children who were treated, 66% had inguinal hernias, 15% hydroceles, 15% undescended testis, and 4% umbilical hernias. Redness or tenderness at the incision site (5.5%), discharge from the surgical wound (1.9%), and wound dehiscence (1.1%) were the main immediate complications after surgery. Overall satisfaction with the cosmetic outcomes of the surgical scar was high, with an average score of 4.73 out of 5 (94.6%).
CONCLUSIONS: Our results demonstrate that administration of N-butyl-2-cyanoacrylate for the closure of small low-tension surgical incisions in the pediatric population is safe, has a low complication rate, and produces excellent cosmetic outcomes.

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Year:  1999        PMID: 10401736     DOI: 10.1016/s1072-7515(99)00068-x

Source DB:  PubMed          Journal:  J Am Coll Surg        ISSN: 1072-7515            Impact factor:   6.113


  10 in total

Review 1.  Use of tissue adhesives in the management of paediatric lacerations.

Authors:  A Mattick
Journal:  Emerg Med J       Date:  2002-09       Impact factor: 2.740

2.  Cyanoacrylate for wound closure in prosthetic vascular graft surgery to prevent infections through contamination.

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Review 3.  Paediatric sutureless circumcision: a systematic literature review.

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Review 4.  Cyanoacrylic tissue glues: Biochemical properties and their usage in urology.

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Journal:  Turk J Urol       Date:  2017-03-01

5.  Comparison of Surgical Outcomes of Laparoscopic Glue and Laparoscopic Suture Hernioplasty in Pediatric Female Inguinal Hernia.

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Journal:  Children (Basel)       Date:  2022-05-15

6.  Glue ablation of a late-presentation urinary fistula after partial nephrectomy.

Authors:  J J Aning; M A Stott; A F Watkinson
Journal:  Br J Radiol       Date:  2009-12       Impact factor: 3.039

7.  To what extent is cyanoacrylate useful to prevent early wound infections in hernia surgery?

Authors:  O Karatepe; A Ozturk; S Koculu; A Cagatay; G Kamali; M Aksoy
Journal:  Hernia       Date:  2008-06-05       Impact factor: 4.739

8.  Efficiency and safety of mesh fixation in laparoscopic inguinal hernia repair using n-butyl cyanoacrylate: long-term biocompatibility in over 1,300 mesh fixations.

Authors:  J F Kukleta; C Freytag; M Weber
Journal:  Hernia       Date:  2011-10-21       Impact factor: 4.739

9.  Quality of scar after total thyroidectomy: a single blinded randomized trial comparing octyl-cyanoacrylate and subcuticular absorbable suture.

Authors:  Fabrizio Consorti; Rosaria Mancuso; Annalisa Piccolo; Eugenio Pretore; Alfredo Antonaci
Journal:  ISRN Surg       Date:  2013-11-12

10.  Cyanoacrylate for Intraoral Wound Closure: A Possibility?

Authors:  Parimala Sagar; Kavitha Prasad; R M Lalitha; Krishnappa Ranganath
Journal:  Int J Biomater       Date:  2015-11-15
  10 in total

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