Literature DB >> 10400337

D-glucosamine propanedithioacetal, an efficient chiral auxiliary in beta-lactam chemistry.

J Anaya1, S D Gero, M Grande, J I Hernando, N M Laso.   

Abstract

The synthesis of some monocyclic beta-lactams (monobactams) by the Staudinger reaction using D-glucosamine propanedithioacetal as chiral auxiliary is reported. The influence of several radicals at C3, C4, and C1' (sugar moiety) as well as other structural aspects are considered in relation to the antielastase activity.

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Year:  1999        PMID: 10400337     DOI: 10.1016/s0968-0896(98)00264-8

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN: 0968-0896            Impact factor:   3.641


  1 in total

1.  Synthesis and antimicrobial activity of some new sugar-based monocyclic beta-lactams.

Authors:  A A Jarrahpour; M Shekarriz; A Taslimi
Journal:  Molecules       Date:  2004-01-31       Impact factor: 4.411

  1 in total

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