Literature DB >> 10400190

Acute myeloid leukemia with t(5;11): two case reports.

M Itoh1, T Okazaki, M Tashima, H Sawada, T Uchiyama.   

Abstract

A case of acute monocytic leukemia (AMoL) with t(5;11)(q31;q23) and a case of acute myelomonocytic leukemia (AMMoL) with t(5;11)(q35;q13.1) are reported. The translocation between the long arm of chromosome 11q and that of chromosome 5q with leukemia have been rarely reported. Though breakpoint of both cases were subtlety different, they had morphologically monocytic character and showed hyperleukocytosis and chemoresistance.

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Year:  1999        PMID： 10400190     DOI： 10.1016/s0145-2126(99)00033-8

Source DB:  PubMed          Journal:  Leuk Res        ISSN： 0145-2126            Impact factor:   3.156


  3 in total

1.  The human GRAF gene is fused to MLL in a unique t(5;11)(q31;q23) and both alleles are disrupted in three cases of myelodysplastic syndrome/acute myeloid leukemia with a deletion 5q.

Authors:  A Borkhardt; S Bojesen; O A Haas; U Fuchs; D Bartelheimer; I F Loncarevic; R M Bohle; J Harbott; R Repp; U Jaeger; S Viehmann; T Henn; P Korth; D Scharr; F Lampert
Journal:  Proc Natl Acad Sci U S A       Date:  2000-08-01       Impact factor: 11.205

2.  A novel insertion ins(18;5)(q21.1;q31.2q35.1) in acute myeloid leukemia associated with microdeletions at 5q31.2, 5q35.1q35.2 and 18q12.3q21.1 detected by oligobased array comparative genomic hybridization.

Authors:  Eigil Kjeldsen
Journal:  Mol Cytogenet       Date:  2014-09-25       Impact factor: 2.009

3.  A Rare t(5;11)(q35;q13) Translocation in an Elderly Patient With Acute Myeloid Leukemia With Maturation: A Case Report.

Authors:  Masahiro Manabe; Yuuji Hagiwara; Reiko Asada; Dai Momose; Yasuyoshi Sugano; Ki-Ryang Koh
Journal:  J Hematol (Brossard)       Date:  2018-05-10
  3 in total

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