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Literature DB >> 10399005

Mechanisms of exogenous antigen presentation by MHC class I molecules in vitro and in vivo: implications for generating CD8+ T cell responses to infectious agents, tumors, transplants, and vaccines.

J W Yewdell¹, C C Norbury, J R Bennink.

Abstract

Entities: Disease Gene

Mesh：

Substances：

Year: 1999 PMID： 10399005 DOI： 10.1016/s0065-2776(08)60785-3

Source DB: PubMed Journal: Adv Immunol ISSN： 0065-2776 Impact factor: 3.543

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57 in total

1. Mobilization of MHC class I molecules from late endosomes to the cell surface following activation of CD34-derived human Langerhans cells.

Authors: P A MacAry; M Lindsay; M A Scott; J I Craig; J P Luzio; P J Lehner
Journal: Proc Natl Acad Sci U S A Date: 2001-03-27 Impact factor: 11.205

2. Restricting expression prolongs expression of foreign genes introduced into animals by retroviruses.

Authors: V B Pinto; S Prasad; J Yewdell; J Bennink; S H Hughes
Journal: J Virol Date: 2000-11 Impact factor: 5.103

3. Antigen processing for MHC class I restricted presentation of exogenous influenza A virus nucleoprotein by B-lymphoblastoid cells.

Authors: J T Voeten; G F Rimmelzwaan; N J Nieuwkoop; R A Fouchier; A D Osterhaus
Journal: Clin Exp Immunol Date: 2001-09 Impact factor: 4.330

4. A macromolecular delivery vehicle for protein-based vaccines: acid-degradable protein-loaded microgels.

Authors: Niren Murthy; Mingcheng Xu; Stephany Schuck; Jun Kunisawa; Nilabh Shastri; Jean M J Fréchet
Journal: Proc Natl Acad Sci U S A Date: 2003-04-18 Impact factor: 11.205

5. Heat-aggregated noninfectious influenza virus induces a more balanced CD8(+)-T-lymphocyte immunodominance hierarchy than infectious virus.

Authors: Yunjung Cho; Sameh Basta; Weisan Chen; Jack R Bennink; Jonathan W Yewdell
Journal: J Virol Date: 2003-04 Impact factor: 5.103

Mechanisms of exogenous antigen presentation by MHC class I molecules in vitro and in vivo: implications for generating CD8+ T cell responses to infectious agents, tumors, transplants, and vaccines.

1. Mobilization of MHC class I molecules from late endosomes to the cell surface following activation of CD34-derived human Langerhans cells.

2. Restricting expression prolongs expression of foreign genes introduced into animals by retroviruses.

3. Antigen processing for MHC class I restricted presentation of exogenous influenza A virus nucleoprotein by B-lymphoblastoid cells.

4. A macromolecular delivery vehicle for protein-based vaccines: acid-degradable protein-loaded microgels.

5. Heat-aggregated noninfectious influenza virus induces a more balanced CD8(+)-T-lymphocyte immunodominance hierarchy than infectious virus.

6. Independence of measles-specific humoral and cellular immune responses to vaccination.

7. Endogenous neosynthesis vs. cross-presentation of viral antigens for cytotoxic T cell priming.

8. Establishment of tumor-associated immunity requires interaction of heat shock proteins with CD91.

9. Human immunodeficiency virus type 1 entry into macrophages mediated by macropinocytosis.

10. T cell homeostatic proliferation elicits effective antitumor autoimmunity.