Literature DB >> 10398112

Serrated adenoma and colorectal cancer.

J R Jass.   

Abstract

Hyperplastic polyps and serrated adenomas of the colorectum show mixed gastrointestinal differentiation, expressing both gastric (M1 or MUC5AC) and intestinal (MUC2) mucins. They also share the phenotype of mild DNA microsatellite instability (MSI-L). Recent findings of clonal genetic changes within hyperplastic polyps fit with a pathway of serrated neoplasia, perhaps culminating in the subset of colorectal cancer characterized by the mild mutator phenotype. Copyright 1999 John Wiley & Sons, Ltd.

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Year:  1999        PMID： 10398112     DOI： 10.1002/(SICI)1096-9896(199904)187:5<499::AID-PATH309>3.0.CO;2-B

Source DB:  PubMed          Journal:  J Pathol        ISSN： 0022-3417            Impact factor:   7.996


  17 in total

1.  Colorectal carcinomas arising in the hyperplastic polyposis syndrome progress through the chromosomal instability pathway.

Authors:  N J Hawkins; P Gorman; I P Tomlinson; P Bullpitt; R L Ward
Journal:  Am J Pathol       Date:  2000-08       Impact factor: 4.307

2.  Novel Vaccine Targeting Colonic Adenoma: a Pre-clinical Model.

Authors:  Toan Pham; Sandra Carpinteri; Shienny Sampurno; Lloyd Pereira; Sara Roth; Vignesh Narasimhan; Phillip Darcy; Jayesh Desai; Alexander G Heriot; Robert G Ramsay
Journal:  J Gastrointest Surg       Date:  2019-01-08       Impact factor: 3.452

3.  Tracing origin of serrated adenomas with BRAF and KRAS mutations.

Authors:  Eui Jin Lee; Chan Choi; Cheol Keun Park; Leeso Maeng; Jehoon Lee; Anhi Lee; Kyoung-Mee Kim
Journal:  Virchows Arch       Date:  2005-07-01       Impact factor: 4.064

4.  Clinicopathological characteristics, microsatellite instability, and expression of mucin core proteins and p53 in colorectal mucinous adenocarcinomas in relation to location.

Authors:  So Yeon Park; Hye Seung Lee; Gheeyoung Choe; Jin Haeng Chung; Woo Ho Kim
Journal:  Virchows Arch       Date:  2006-04-28       Impact factor: 4.064

5.  Loss of the Association between Telomere Length and Mitochondrial DNA Copy Number Contribute to Colorectal Carcinogenesis.

Authors:  Hyunsu Lee; Ji-Hyoung Cho; Won-Jin Park; Soo-Jung Jung; In-Jang Choi; Jae-Ho Lee
Journal:  Pathol Oncol Res       Date:  2017-05-09       Impact factor: 3.201

6.  Over-expression of cathepsin E and trefoil factor 1 in sessile serrated adenomas of the colorectum identified by gene expression analysis.

Authors:  Maria Caruso; James Moore; Gregory J Goodall; Michelle Thomas; Stuart Phillis; Anna Tyskin; Glenice Cheetham; Nancy Lerda; Hiroyuki Takahashi; Andrew Ruszkiewicz
Journal:  Virchows Arch       Date:  2009-01-27       Impact factor: 4.064

7.  BRAF mutation is associated with DNA methylation in serrated polyps and cancers of the colorectum.

Authors:  T Kambara; L A Simms; V L J Whitehall; K J Spring; C V A Wynter; M D Walsh; M A Barker; S Arnold; A McGivern; N Matsubara; N Tanaka; T Higuchi; J Young; J R Jass; B A Leggett
Journal:  Gut       Date:  2004-08       Impact factor: 23.059

8.  Evaluation of magnifying colonoscopy in the diagnosis of serrated polyps.

Authors:  Shinya Ishigooka; Masahito Nomoto; Nobuyuki Obinata; Yoshichika Oishi; Yoshinori Sato; Satoko Nakatsu; Midori Suzuki; Yoshiko Ikeda; Tadateru Maehata; Tomoaki Kimura; Yoshiyuki Watanabe; Takashi Nakajima; Hiro-o Yamano; Hiroshi Yasuda; Fumio Itoh
Journal:  World J Gastroenterol       Date:  2012-08-28       Impact factor: 5.742

9.  Juvenile polyps have gastric differentiation with MUC5AC expression and downregulation of CDX2 and SMAD4.

Authors:  Rita Barros; Nuno Mendes; James R Howe; Celso A Reis; Carme de Bolos; Fátima Carneiro; Leonor David; Raquel Almeida
Journal:  Histochem Cell Biol       Date:  2009-03-06       Impact factor: 4.304

Review 10.  Serrated neoplasia of the colorectum.

Authors:  Nathan T Harvey; Andrew Ruszkiewicz
Journal:  World J Gastroenterol       Date:  2007-07-28       Impact factor: 5.742
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