Literature DB >> 10395515

Pikuroside: a novel iridoid from Picrorhiza kurroa.

Q Jia1, M F Hong, D Minter.   

Abstract

A new iridoid, pikuroside (1), was isolated from the roots of Picrorhiza kurroa, together with three known iridoids, picroside I (2), picroside II (3), and 6-feruloyl catalpol (4). The structure of 1 was established by interpretation and full assignments of NMR spectral data. Pikuroside (1) had no antiinflammatory activity, although the crude extract and picroside II (3) demonstrated moderate activity.

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Year:  1999        PMID: 10395515     DOI: 10.1021/np980493+

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  6 in total

1.  Bioactive Compounds from Medicinal Plants in Myanmar.

Authors:  Nwet Nwet Win; Hiroyuki Morita
Journal:  Prog Chem Org Nat Prod       Date:  2021

2.  Modification of cysteine residue in p65 subunit of nuclear factor-kappaB (NF-kappaB) by picroliv suppresses NF-kappaB-regulated gene products and potentiates apoptosis.

Authors:  Preetha Anand; Ajaikumar B Kunnumakkara; Kuzhuvelil B Harikumar; Kwang Seok Ahn; Vladimir Badmaev; Bharat B Aggarwal
Journal:  Cancer Res       Date:  2008-11-01       Impact factor: 12.701

Review 3.  Anti-inflammatory iridoids of botanical origin.

Authors:  A Viljoen; N Mncwangi; I Vermaak
Journal:  Curr Med Chem       Date:  2012       Impact factor: 4.530

4.  A Picrorhiza kurroa derivative, picroliv, attenuates the development of dextran-sulfate-sodium-induced colitis in mice.

Authors:  De-Kui Zhang; Jian-Jie Yu; Yu-Min Li; Li-Na Wei; Yi Yu; Yan-Hu Feng; Xiang Wang
Journal:  Mediators Inflamm       Date:  2012-10-16       Impact factor: 4.711

5.  Molecular characterization of UGT94F2 and UGT86C4, two glycosyltransferases from Picrorhiza kurrooa: comparative structural insight and evaluation of substrate recognition.

Authors:  Wajid Waheed Bhat; Niha Dhar; Sumeer Razdan; Satiander Rana; Rukmankesh Mehra; Amit Nargotra; Rekha S Dhar; Nasheeman Ashraf; Ram Vishwakarma; Surrinder K Lattoo
Journal:  PLoS One       Date:  2013-09-16       Impact factor: 3.240

6.  Demand, End-Uses, and Conservation of Alpine Medicinal Plant Neopicrorhiza scrophulariiflora (Pennell) D. Y. Hong in Central Himalaya.

Authors:  Gandhiv Kafle; Indira Bhattarai Sharma; Mohan Siwakoti; Arjun Kumar Shrestha
Journal:  Evid Based Complement Alternat Med       Date:  2018-06-19       Impact factor: 2.629

  6 in total

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