Literature DB >> 10395514

Guiaflavine, a new bisindole quaternary alkaloid from the stem bark of Strychnos guianensis.

J Penelle1, M Tits, P Christen, V Brandt, M Frédérich, L Angenot.   

Abstract

A reinvestigation of Strychnos guianensis resulted in the isolation of a colored quaternary bisindole alkaloid from the stem bark. The structure of this new substance, guiaflavine (1), was defined by detailed spectroscopic methods and comparison with model compounds.

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Year:  1999        PMID： 10395514     DOI： 10.1021/np9804738

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  2 in total

1.  Bisindole alkaloids from Strychnos guianensis are effective antagonists of nicotinic acetylcholine receptors in cultured human TE671 cells.

Authors:  Pierre Wins; Ilca Margineanu; Jacques Penelle; Luc Angenot; Thierry Grisar; Lucien Bettendorff
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2003-02-19       Impact factor: 3.000

2.  Formal Alder-ene reaction of a bicyclo[1.1.0]butane in the synthesis of the tricyclic quaternary ammonium core of daphniglaucins.

Authors:  Masafumi Ueda; Maciej A A Walczak; Peter Wipf
Journal:  Tetrahedron Lett       Date:  2008-06       Impact factor: 2.415
  2 in total

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