Literature DB >> 10395513

Characterization of 6-epi-3-anhydroophiobolin B from Cochliobolus heterostrophus.

X Shen1, S B Krasnoff, S W Lu, C D Dunbar, J O'Neal, B G Turgeon, O C Yoder, D M Gibson, M T Hamann.   

Abstract

The new sesterterpenoid 6-epi-3-anhydroophiobolin B (1) and six known ophiobolins were isolated from the extracts of the fungus Cochliobolus heterostrophus race O. The structure of 6-epi-3-anhydroophiobolin B was deduced from analysis of spectral data and the structural characterization of dehydration and dimerization products. Ophiobolin A (2) showed potent activity in cytotoxicity assays and marginal activity in antimalarial assays.

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Year:  1999        PMID： 10395513     DOI： 10.1021/np980462e

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  3 in total

Review 1.  The Biological Activities of Sesterterpenoid-Type Ophiobolins.

Authors:  Wei Tian; Zixin Deng; Kui Hong
Journal:  Mar Drugs       Date:  2017-07-18       Impact factor: 5.118

2.  The Biosynthesis and Transport of Ophiobolins in Aspergillus ustus 094102.

Authors:  Jingjing Yan; Jiamin Pang; Jianjia Liang; Wulin Yu; Xuequn Liao; Ayikaimaier Aobulikasimu; Xinrui Yi; Yapeng Yin; Zixin Deng; Kui Hong
Journal:  Int J Mol Sci       Date:  2022-02-08       Impact factor: 5.923

Review 3.  Anticancer and antifungal compounds from Aspergillus, Penicillium and other filamentous fungi.

Authors:  Tanja Thorskov Bladt; Jens Christian Frisvad; Peter Boldsen Knudsen; Thomas Ostenfeld Larsen
Journal:  Molecules       Date:  2013-09-13       Impact factor: 4.411
  3 in total

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