Literature DB >> 10393463

Diabetic neuropathic foot ulcer: successful treatment by low-intensity laser therapy.

A Schindl1, M Schindl, H Pernerstorfer-Schön, K Kerschan, R Knobler, L Schindl.   

Abstract

OBJECTIVE: To evaluate the efficacy of low-intensity laser irradiation for the induction of wound healing of a diabetic neuropathic foot ulcer. CASE: We report a case of a man with insulin-dependent diabetes mellitus, sensory neuropathy, macroangiopathy and microangiopathy who had been suffering from an ulcer of his first left toe accompanied by osteomyelitis for 6 weeks.
RESULTS: After a total of 16 sessions of low-intensity laser therapy using a 670-nm diode laser administered within a 4-week period the ulcer healed completely. During a follow-up period of 9 months, there was no recurrence of the ulcer even though the patient's metabolic condition remained unstable.
CONCLUSIONS: Although laser therapy was not applied as a monotherapy, the present observation suggests that it might constitute a useful side-effect-free alternative treatment modality for the induction of wound healing of neuropathic ulcers in diabetic patients. Therefore large properly controlled randomized studies seem justified.

Entities:  

Mesh:

Year:  1999        PMID: 10393463     DOI: 10.1159/000018140

Source DB:  PubMed          Journal:  Dermatology        ISSN: 1018-8665            Impact factor:   5.366


  12 in total

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Authors:  José Carlos Tatmatsu-Rocha; Carla Roberta Tim; Lucimar Avo; Rubens Bernardes-Filho; Patricia Brassolatti; Hueliton Wilian Kido; Michael R Hamblin; Nivaldo Antonio Parizotto
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6.  [Venous leg ulcers: no improvement of wound healing with 685-nm low level laser therapy. Randomised, placebo-controlled, double-blind study].

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7.  Laser light influences cellular viability and proliferation in diabetic-wounded fibroblast cells in a dose- and wavelength-dependent manner.

Authors:  N N Houreld; H Abrahamse
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8.  Low-level laser therapy rescues dendrite atrophy via upregulating BDNF expression: implications for Alzheimer's disease.

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9.  Low-level laser therapy regulates microglial function through Src-mediated signaling pathways: implications for neurodegenerative diseases.

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Journal:  J Neuroinflammation       Date:  2012-09-18       Impact factor: 8.322

Review 10.  New treatments for diabetic neuropathic foot ulceration: views from a wound healing unit.

Authors:  Dean T Williams; Keith G Harding
Journal:  Curr Diab Rep       Date:  2003-12       Impact factor: 5.430

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