Literature DB >> 10391773

The extraterrestrial origin of the homochirality of biomolecules--rebuttal to a critique.

W A Bonner1, J M Greenberg, E Rubenstein.   

Abstract

Having concluded that abiotic terrestrial mechanisms would have been ineffectual for the origin of terrestrial homochirality, we have proposed an alternative extraterrestrial scenario involving stereoselective ultraviolet photolysis of the racemic constituents of interstellar grain mantles by circularly polarized synchrotron radiation from neutron stars, followed by terrestrial accretion of the resulting chiral molecules via cometary impact. Recently L. Keszthelyi (1995) has reviewed a number of our arguments and advanced several erroneous calculations and conclusions purporting to negate them. We offer here points of rebuttal to Keszthelyi's criticisms, and support our inferences with recent data regarding indigenous enantiomeric excesses of L-amino acids in the Murchison meteorite.

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Year:  1999        PMID: 10391773     DOI: 10.1023/a:1006544203107

Source DB:  PubMed          Journal:  Orig Life Evol Biosph        ISSN: 0169-6149            Impact factor:   1.950


  8 in total

1.  Carbon isotope composition of individual amino acids in the Murchison meteorite.

Authors:  M H Engel; S A Macko; J A Silfer
Journal:  Nature       Date:  1990-11-01       Impact factor: 49.962

Review 2.  The origin and amplification of biomolecular chirality.

Authors:  W A Bonner
Journal:  Orig Life Evol Biosph       Date:  1991       Impact factor: 1.950

Review 3.  Origin of the homochirality of biomolecules.

Authors:  L Keszthelyi
Journal:  Q Rev Biophys       Date:  1995-11       Impact factor: 5.318

4.  Supernovae, neutron stars and biomolecular chirality.

Authors:  W A Bonner; E Rubenstein
Journal:  Biosystems       Date:  1987       Impact factor: 1.973

5.  Asymmetric photolysis of (RS)-leucine with circularly polarized ultraviolet light.

Authors:  J J Flores; W A Bonner; G A Massey
Journal:  J Am Chem Soc       Date:  1977-05-25       Impact factor: 15.419

6.  Comet Halley as an aggregate of interstellar dust and further evidence for the photochemical formation of organics in the interstellar medium.

Authors:  R Briggs; G Ertem; J P Ferris; J M Greenberg; P J McCain; C X Mendoza-Gomez; W Schutte
Journal:  Orig Life Evol Biosph       Date:  1992       Impact factor: 1.950

7.  The seeding of life by comets.

Authors:  J M Greenberg; C X Mendoza-Gomez
Journal:  Adv Space Res       Date:  1992       Impact factor: 2.152

8.  Enantiomeric excesses in meteoritic amino acids.

Authors:  J R Cronin; S Pizzarello
Journal:  Science       Date:  1997-02-14       Impact factor: 47.728

  8 in total
  5 in total

1.  Homochirality of biomolecules: counter-arguments against critical notes.

Authors:  L Keszthelyi
Journal:  Orig Life Evol Biosph       Date:  2001-06       Impact factor: 1.950

2.  On the origin of terrestrial homochirality for nucleosides and amino acids.

Authors:  Ronald Breslow; Zhan-Ling Cheng
Journal:  Proc Natl Acad Sci U S A       Date:  2009-05-28       Impact factor: 11.205

3.  Unexpected differences between D- and L- tyrosine lead to chiral enhancement in racemic mixtures.

Authors:  Meir Shinitzky; Fabio Nudelman; Yaniv Barda; Rachel Haimovitz; Effie Chen; David W Deamer
Journal:  Orig Life Evol Biosph       Date:  2002-08       Impact factor: 1.950

4.  Imitating prebiotic homochirality on Earth.

Authors:  Ronald Breslow; Mindy Levine; Zhan-Ling Cheng
Journal:  Orig Life Evol Biosph       Date:  2009-11-13       Impact factor: 1.950

Review 5.  Data-Driven Astrochemistry: One Step Further within the Origin of Life Puzzle.

Authors:  Alexander Ruf; Louis L S d'Hendecourt; Philippe Schmitt-Kopplin
Journal:  Life (Basel)       Date:  2018-06-01
  5 in total

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