Literature DB >> 10391343

Spinal cord protection in descending thoracic and thoracoabdominal aortic repair.

H J Safi1, C C Miller.   

Abstract

BACKGROUND: During simple cross-clamp repair of the descending thoracic or thoracoabdominal aorta, the likelihood of neurologic complications increases greatly after only 30 minutes of spinal cord ischemia. At greatest risk are patients with type II thoracoabdominal aortic aneurysms.
METHODS: We reviewed our experience of simple cross-clamp repair and procedures accompanied by adjuncts, paying particular attention to the outcome of patients who had type II thoracoabdominal aortic aneurysms. Between February 1991 and March 1998, 508 patients had descending thoracic and thoracoabdominal aortic repair, 255 (50.2%) of whom received the adjuncts of cerebrospinal fluid drainage and distal aortic perfusion.
RESULTS: Fifteen patients died on the day of operation and could not be evaluated for neurologic deficit. The overall incidence of neurologic deficit was 33 of 493 patients (6.7%). In patients who received adjuncts, neurologic deficit occurred in 9 of 247 (3.6%) overall; in types I and II it was 8 of 164 (4.9%), and in type II alone, 7 of 87 (8.1%). Neurologic deficit in simple cross-clamp patients was 24 of 246 (9.8%) overall; in types I and II it was 15 of 99 (15.2%), and in type II alone, 13 of 44 (29.6%).
CONCLUSIONS: With the surgical adjuncts of cerebrospinal fluid drainage and distal aortic perfusion, the probability of neurologic deficit is lowered appreciably.

Entities:  

Mesh:

Year:  1999        PMID: 10391343     DOI: 10.1016/s0003-4975(99)00397-5

Source DB:  PubMed          Journal:  Ann Thorac Surg        ISSN: 0003-4975            Impact factor:   4.330


  16 in total

Review 1.  Heat shock proteins as biomarkers for the rapid detection of brain and spinal cord ischemia: a review and comparison to other methods of detection in thoracic aneurysm repair.

Authors:  James G Hecker; Michael McGarvey
Journal:  Cell Stress Chaperones       Date:  2010-08-30       Impact factor: 3.667

2.  Thoracoabdominal aortic aneurysm.

Authors:  John R Frederick; Y Joseph Woo
Journal:  Ann Cardiothorac Surg       Date:  2012-09

3.  Heat shock proteins HSP70 and HSP27 in the cerebral spinal fluid of patients undergoing thoracic aneurysm repair correlate with the probability of postoperative paralysis.

Authors:  James G Hecker; Hari Sundram; Shaomin Zou; Amy Praestgaard; Joseph E Bavaria; Sindhu Ramchandren; Michael McGarvey
Journal:  Cell Stress Chaperones       Date:  2008-04-17       Impact factor: 3.667

Review 4.  [Thoracic aorta aneurysms].

Authors:  I Akin; S Kische; H Schneider; H Ince; C A Nienaber
Journal:  Internist (Berl)       Date:  2009-08       Impact factor: 0.743

Review 5.  [Thoracoabominal aortic aneurysms-endovascular options].

Authors:  M Gschwendtner
Journal:  Radiologe       Date:  2018-09       Impact factor: 0.635

6.  Improved outcome in thoracoabdominal aortic aneurysm repair: the role of cerebrospinal fluid drainage.

Authors:  Tatjana M Fleck; Herbert Koinig; Reinhard Moidl; Martin Czerny; Carole Hamilton; Arno Schifferer; Marian Jelen; Ernst Wolner; Martin Grabenwoger
Journal:  Neurocrit Care       Date:  2005       Impact factor: 3.210

Review 7.  Review of Treatment for Thoracoabdominal Aortic Aneurysm, and the Modern Experience of Multi-Branched Endograft in Taiwan.

Authors:  Ting Chao Lin; Chun Che Shih
Journal:  Acta Cardiol Sin       Date:  2017-01       Impact factor: 2.672

Review 8.  Endovascular versus conventional open surgical repair for thoracoabdominal aortic aneurysms.

Authors:  Sherif Sultan; Jamie Concannon; Dave Veerasingam; Wael Tawfick; Peter McHugh; Fionnuala Jordan; Niamh Hynes
Journal:  Cochrane Database Syst Rev       Date:  2022-04-01

Review 9.  Thoracoabdominal aortic aneurysm repair: open, endovascular, or hybrid?

Authors:  Joshua M Rosenblum; Edward P Chen
Journal:  Gen Thorac Cardiovasc Surg       Date:  2017-08-30

10.  Early adenosine receptor activation ameliorates spinal cord reperfusion injury.

Authors:  T Brett Reece; Curtis G Tribble; David O Okonkwo; Jonathon D Davis; Thomas S Maxey; Leo M Gazoni; Joel Linden; Irving L Kron; John A Kern
Journal:  J Cardiovasc Med (Hagerstown)       Date:  2008-04       Impact factor: 2.160

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