Literature DB >> 10390240

In vitro activity of HSR-903, a new oral quinolone, against bacteria causing respiratory infections.

A Watanabe1, Y Tokue, H Takahashi, T Kikuchi, T Kobayashi, K Gomi, S Fujimura, T Nukiwa.   

Abstract

The in vitro activity of HSR-903, an oral quinolone, against 196 recent clinical isolates of respiratory pathogens was evaluated. HSR-903 was 2 to 32 times more active than ofloxacin, ciprofloxacin, and sparfloxacin against Staphylococcus aureus, including methicillin-resistant strains, and Streptococcus pneumoniae and was at least as active as the other quinolones against gram-negative pathogens.

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Year:  1999        PMID: 10390240      PMCID: PMC89361     

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  2 in total

1.  In vivo activity of HSR-903, a new fluoroquinolone, against respiratory pathogens.

Authors:  S Yoshizumi; H Domon; S Miyazaki; K Yamaguchi
Journal:  Antimicrob Agents Chemother       Date:  1998-04       Impact factor: 5.191

2.  In vitro activity of HSR-903, a new quinolone.

Authors:  Y Takahashi; N Masuda; M Otsuki; M Miki; T Nishino
Journal:  Antimicrob Agents Chemother       Date:  1997-06       Impact factor: 5.191

  2 in total
  3 in total

1.  Comparative in vitro antimicrobial activities of the newly synthesized quinolone HSR-903, sitafloxacin (DU-6859a), gatifloxacin (AM-1155), and levofloxacin against Mycobacterium tuberculosis and Mycobacterium avium complex.

Authors:  H Tomioka; K Sato; T Akaki; H Kajitani; S Kawahara; M Sakatani
Journal:  Antimicrob Agents Chemother       Date:  1999-12       Impact factor: 5.191

Review 2.  A critical review of the fluoroquinolones: focus on respiratory infections.

Authors:  George G Zhanel; Kelly Ennis; Lavern Vercaigne; Andrew Walkty; Alfred S Gin; John Embil; Heather Smith; Daryl J Hoban
Journal:  Drugs       Date:  2002       Impact factor: 9.546

Review 3.  Multidrug-resistant Streptococcus pneumoniae infections: current and future therapeutic options.

Authors:  Françoise Van Bambeke; René R Reinert; Peter C Appelbaum; Paul M Tulkens; Willy E Peetermans
Journal:  Drugs       Date:  2007       Impact factor: 9.546

  3 in total

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