Literature DB >> 10389838

Comparative genetics of type 1 diabetes and autoimmune disease: common loci, common pathways?

K G Becker1.   

Abstract

Genome-scale analysis in type 1 diabetes has resulted in a number of non-major histocompatibility complex loci of varying levels of statistical significance. In no case has a specific gene been proven to be the source of genetic linkage at any candidate locus. Comparative analysis of the position of loci for type 1 diabetes with candidate loci from other autoimmune/inflammatory diseases shows considerable overlap. This supports a hypothesis that the underlying genetic susceptibility to type 1 diabetes may be shared with other clinically distinct autoimmune diseases such as systemic lupus erythemastosus, multiple sclerosis, and Crohn's Disease.

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Year:  1999        PMID： 10389838     DOI： 10.2337/diabetes.48.7.1353

Source DB:  PubMed          Journal:  Diabetes        ISSN： 0012-1797            Impact factor:   9.461


  14 in total

Review 1.  Polyspecificity of autoimmune responses in type 1 (autoimmune) diabetes.

Authors:  L M Esteban; A G Baxter
Journal:  Clin Exp Immunol       Date:  2001-11       Impact factor: 4.330

2.  Meta-analysis of TYK2 gene polymorphisms association with susceptibility to autoimmune and inflammatory diseases.

Authors:  Jin-Hui Tao; Yan-Feng Zou; Xiao-Liang Feng; Jing Li; Fang Wang; Fan-Ming Pan; Dong-Qing Ye
Journal:  Mol Biol Rep       Date:  2010-12-08       Impact factor: 2.316

3.  Gene polymorphisms of interleukin-4, interleukin-10 and transforming growth factor-beta in Graves' disease.

Authors:  Omid Khalilzadeh; Mehdi Anvari; Fatemeh Momen-Heravi; Alireza Esteghamati; Armin Rashidi; Mahdi Mahmoudi; Behrouz Nikbin; Aliakbar Amirzargar
Journal:  Clin Exp Med       Date:  2009-10-31       Impact factor: 3.984

4.  Associations between the FAS -670 A/G and -1,377 G/A polymorphisms and susceptibility to autoimmune rheumatic diseases: a meta-analysis.

Authors:  Young Ho Lee; Sang-Cheol Bae; Sung Jae Choi; Jong Dae Ji; Gwan Gyu Song
Journal:  Mol Biol Rep       Date:  2012-10-05       Impact factor: 2.316

5.  Association of the NFKBIA gene polymorphisms with susceptibility to autoimmune and inflammatory diseases: a meta-analysis.

Authors:  Guo-Long Zhang; Yan-Feng Zou; Xiao-Liang Feng; He-Jian Shi; Xu-Feng Du; Min-Hua Shao; Yong Gu; Qing Zhou
Journal:  Inflamm Res       Date:  2010-05-21       Impact factor: 4.575

6.  Beta-cell, thyroid, gastric, adrenal and coeliac autoimmunity and HLA-DQ types in type 1 diabetes.

Authors:  C E De Block; I H De Leeuw; J J Vertommen; R P Rooman; M V Du Caju; C M Van Campenhout; J J Weyler; F Winnock; J Van Autreve; F K Gorus
Journal:  Clin Exp Immunol       Date:  2001-11       Impact factor: 4.330

7.  Common genetic determinants of uveitis shared with other autoimmune disorders.

Authors:  Mary J Mattapallil; Azize Sahin; Phyllis B Silver; Shu-Hui Sun; Chi-Chao Chan; Elaine F Remmers; J Fielding Hejtmancik; Rachel R Caspi
Journal:  J Immunol       Date:  2008-05-15       Impact factor: 5.422

8.  Peripheral blood gene expression patterns discriminate among chronic inflammatory diseases and healthy controls and identify novel targets.

Authors:  Bertalan Mesko; Szilard Poliska; Andrea Szegedi; Zoltan Szekanecz; Karoly Palatka; Maria Papp; Laszlo Nagy
Journal:  BMC Med Genomics       Date:  2010-05-05       Impact factor: 3.063

Review 9.  Association between FCGR3B copy number variations and susceptibility to autoimmune diseases: a meta-analysis.

Authors:  Young Ho Lee; Sang-Cheol Bae; Young Ho Seo; Jae-Hoon Kim; Sung Jae Choi; Jong Dae Ji; Gwan Gyu Song
Journal:  Inflamm Res       Date:  2015-09-25       Impact factor: 4.575

10.  Study design of the Trial to Reduce IDDM in the Genetically at Risk (TRIGR).

Authors: 
Journal:  Pediatr Diabetes       Date:  2007-06       Impact factor: 4.866
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