Literature DB >> 10389275

Limonoids from fruit of Melia toosendan and their cytotoxic activity.

K Tada1, M Takido, S Kitanaka.   

Abstract

Two new limonoids, toosendanal and 12-O-methylvolkensin, were isolated from the fruits of Melia toosendan Sieb. et Zucc. along with three known limonoids, meliatoxin B1, trichillin H, and toosendanin. The structures of the new limonoids were established by spectroscopic methods, with toosendanal having C-1/C-29 and C-19/C-29 acetal bridges. Both meliatoxin B1 and toosendanin exhibit cytotoxic activity against KB cells.

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Year:  1999        PMID: 10389275     DOI: 10.1016/s0031-9422(99)00115-6

Source DB:  PubMed          Journal:  Phytochemistry        ISSN: 0031-9422            Impact factor:   4.072


  14 in total

1.  Plant-growth inhibitory activity of cedrelanolide from Cedrela salvadorensis.

Authors:  C L Céspedes; J S Calderón; J R Salazar; B Lotina-Hennsen; R Segura
Journal:  J Chem Ecol       Date:  2001-01       Impact factor: 2.626

2.  Growth inhibition and apoptosis-induced effect on human cancer cells of toosendanin, a triterpenoid derivative from chinese traditional medicine.

Authors:  Bin Zhang; Zhong-Feng Wang; Mian-Zhi Tang; Yu-Liang Shi
Journal:  Invest New Drugs       Date:  2005-12       Impact factor: 3.850

3.  Inhibitory effect of a triterpenoid compound, with or without alpha interferon, on hepatitis C virus infection.

Authors:  Takako Watanabe; Naoya Sakamoto; Mina Nakagawa; Sei Kakinuma; Yasuhiro Itsui; Yuki Nishimura-Sakurai; Mayumi Ueyama; Yusuke Funaoka; Akiko Kitazume; Sayuri Nitta; Kei Kiyohashi; Miyako Murakawa; Seishin Azuma; Kiichiro Tsuchiya; Shinya Oooka; Mamoru Watanabe
Journal:  Antimicrob Agents Chemother       Date:  2011-03-28       Impact factor: 5.191

4.  The pre-synaptic blocker toosendanin does not inhibit secretion in exocrine cells.

Authors:  Zong-Jie Cui; Xue-Hui He
Journal:  World J Gastroenterol       Date:  2002-10       Impact factor: 5.742

5.  In silico estrogen receptor alpha antagonist studies and toxicity prediction of Melia azedarach leaves bioactive ethyl acetate fraction.

Authors:  Martha Ervina; Mohammad Rizki Fadhil Pratama; Hadi Poerwono; Juni Ekowati; Retno Widyowati; Katsuyoshi Matsunami
Journal:  J Adv Pharm Technol Res       Date:  2021-07-16

6.  Potent and broad anticancer activities of leaf extracts from Melia azedarach L. of the subtropical Okinawa islands.

Authors:  Kuniaki Nerome; Taku Ito-Kureha; Tiziana Paganini; Takao Fukuda; Yasuhiro Igarashi; Hiroto Ashitomi; Shinya Ikematsu; Tadashi Yamamoto
Journal:  Am J Cancer Res       Date:  2020-02-01       Impact factor: 6.166

7.  Identification of potential modulators of osteosarcoma metastasis by high-throughput cellular screening of natural products.

Authors:  Sarah A Long; Shan Huang; Anusha Kambala; Ling Ren; Jennifer Wilson; Michael Goetz; Xiaojiang Hao; Xiaosheng Yang; Ekaterina I Goncharova; Libin Jia; Amy LeBlanc; Chand Khanna; Curtis J Henrich; John A Beutler
Journal:  Chem Biol Drug Des       Date:  2020-07-28       Impact factor: 2.873

8.  Ethanolic Extract of Melia Fructus Has Anti-influenza A Virus Activity by Affecting Viral Entry and Viral RNA Polymerase.

Authors:  Young-Hee Jin; Jang-Gi Choi; Won-Kyung Cho; Jin Yeul Ma
Journal:  Front Microbiol       Date:  2017-03-28       Impact factor: 5.640

9.  Cytotoxic tirucallane triterpenoids from Melia azedarach fruits.

Authors:  Nikoletta G Ntalli; Filippo Cottiglia; Carlos A Bueno; Laura E Alché; Marco Leonti; Simona Vargiu; Ersilia Bifulco; Urania Menkissoglu-Spiroudi; Pierluigi Caboni
Journal:  Molecules       Date:  2010-08-27       Impact factor: 4.411

10.  Meliacarpinin-Type Limonoids from the Bark of Melia toosendan.

Authors:  Yalin Hu; Li Heng; Rong Xu; Junhe Li; Shanshan Wei; Deran Xu; Jun Luo; Yi Li
Journal:  Molecules       Date:  2018-10-10       Impact factor: 4.411

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