Literature DB >> 10386719

The benefit of Beam's eye view based 3D treatment planning for cervical cancer.

N Gerstner1, S Wachter, T H Knocke, C Fellner, A Wambersie, R Pötter.   

Abstract

PURPOSE: The aim of this study was to evaluate the possibility of Beam's eye view (BEV) based three dimensional (3D) treatment planning, to reduce portions of organs at risk included in the treated volume without increasing the risk of geographical miss in external beam therapy of cervical cancer.
MATERIALS AND METHODS: Three dimensional dose distribution of BEV based 3D treatment plans was compared to the 3D dose distribution derived from a four-field-box-technique using standard portals. A total of 20 patients with cervical cancer stage FIGO IIB and FIGO IIIB was included. Dose distribution in the target volumes and in the organs at risk of BEV based treatment planning, was compared to the dose distribution of the standard field technique using dose-volume-histograms.
RESULTS: In 4/20 patients (20%) a geographical miss at the cervix uteri was observed for the standard field technique. The BEV based treatment planning resulted in an adequate coverage of target volume and additionally in a reduction of portions of bladder and bowel volume included in the treated volume (-13.5, -10%). In contrast the BEV based technique resulted in an increase of portions of the rectum volume included in the treated volume compared to standard portals due to a shift of the rectum by the enlarged cervix uteri from its posterior to a lateral position. An overall 7% reduction of treated volume was observed, although the maximum width of lateral fields increased for the BEV technique. Moreover, we have found a remarkable impact of bladder fillings on the amount of bowel and bladder volume included in the treated volume.
CONCLUSION: BEV based 3D treatment planning for external beam therapy of cervical cancer offers a possibility to avoid geographical miss of part of the CTV with reduced portions of bladder and bowel volume included in the treated volume.

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Year:  1999        PMID: 10386719     DOI: 10.1016/s0167-8140(99)00038-9

Source DB:  PubMed          Journal:  Radiother Oncol        ISSN: 0167-8140            Impact factor:   6.280


  6 in total

1.  Dose-Escalated Intensity-Modulated Radiotherapy for the Management of Locally Advanced Cervical Cancer.

Authors:  Balaji Shewalkar; Asfiya Khan; Dnyanda Yerlekar; Jitendra Patel; Hrishikesh Khadilkar; Rajakumar Sakthivel; Reeta Kataruka
Journal:  Cureus       Date:  2022-06-15

2.  Internal target volume for post-hysterectomy vaginal recurrences of cervical cancers during image-guided radiotherapy.

Authors:  Maheshkumar N Upasani; Supriya Chopra; Reena Engineer; Umesh Mahantshetty; Seema Medhi; Zubin Mehta; Shyam K Shrivastava
Journal:  Br J Radiol       Date:  2015-08-07       Impact factor: 3.039

Review 3.  The use of MRI in planning radiotherapy for gynaecological tumours.

Authors:  I Barillot; A Reynaud-Bougnoux
Journal:  Cancer Imaging       Date:  2006-06-22       Impact factor: 3.909

Review 4.  Advances in Radiation Oncology for the Treatment of Cervical Cancer.

Authors:  Mame Daro Faye; Joanne Alfieri
Journal:  Curr Oncol       Date:  2022-02-09       Impact factor: 3.677

Review 5.  Dosimetric comparison of intensity modulated radiotherapy and three-dimensional conformal radiotherapy in patients with gynecologic malignancies: a systematic review and meta-analysis.

Authors:  Baojuan Yang; Lin Zhu; Haiyan Cheng; Qi Li; Yunyan Zhang; Yashuang Zhao
Journal:  Radiat Oncol       Date:  2012-11-23       Impact factor: 3.481

6.  Better survival with three-dimensional conformal radiotherapy than with conventional radiotherapy for cervical cancer: a population-based study.

Authors:  Chen-Hsi Hsieh; Shiang-Jiun Tsai; Wen-Yen Chiou; Moon-Sing Lee; Hon-Yi Lin; Shih-Kai Hung
Journal:  ISRN Oncol       Date:  2013-10-02
  6 in total

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