Literature DB >> 103866

Purine nucleoside phosphorylase in lymphocytes of various mammalian species.

M Borgers, F Thone.   

Abstract

The distribution of purine nucleoside phosphorylase has been assessed by light and electron microscopy in peripheral lymphocytes of man, the rabbit, rat, mouse, guinea-pig, pig and dog. The enzyme activity was detected in the cytosol of the majority of lymphocytes in all species. The amount of reaction product was high in the rabbit, man, guinea-pig and dog, mpderate in the rat and very low in the pig and mouse. Other blood cell types are reactive as well, although there is a variation between species. A possible relationship of purine nucleoside phosphorylase with particular subpopulations of lymphocytes is suggested.

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Year:  1978        PMID： 103866     DOI： 10.1007/bf01003121

Source DB:  PubMed          Journal:  Histochem J        ISSN： 0018-2214


  16 in total

1.  Lymphospecific toxicity in adenosine deaminase deficiency and purine nucleoside phosphorylase deficiency: possible role of nucleoside kinase(s).

Authors:  D A Carson; J Kaye; J E Seegmiller
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205

2.  Nucleoside phosphorylase activity in blood vessels and formed elements of the blood of the dog.

Authors:  M Borgers; J Schaper; W Schaper
Journal:  J Histochem Cytochem       Date:  1972-12       Impact factor: 2.479

3.  The role of the recirculating thymus-dependent lymphocyte in resistance to Trichostrongylus colubriformis in the guinea-pig.

Authors:  J K Dineen; D B Adams
Journal:  Immunology       Date:  1971-01       Impact factor: 7.397

4.  Nucleoside phosphorylase: localization and role in the myocardial distribution of purines.

Authors:  V R Rubio; T Wiedmeier; R M Berne
Journal:  Am J Physiol       Date:  1972-03

5.  Separation of leukocytes from blood and bone marrow. Introduction.

Authors:  A Böyum
Journal:  Scand J Clin Lab Invest Suppl       Date:  1968

6.  The early stages of absorption of injected horseradish peroxidase in the proximal tubules of mouse kidney: ultrastructural cytochemistry by a new technique.

Authors:  R C Graham; M J Karnovsky
Journal:  J Histochem Cytochem       Date:  1966-04       Impact factor: 2.479

7.  An abnormal form of purine nucleoside phosphorylase in a family with a child with severe defective T-cell-and normal B-cell immunity.

Authors:  L H van Heukelom; G E Staal; J W Stoop; B J Zegers
Journal:  Clin Chim Acta       Date:  1976-10-01       Impact factor: 3.786

8.  Purine nucleoside phosphorylase deficiency. Evidence for molecular heterogeneity in two families with enzyme-deficient members.

Authors:  W R Osborne; S H Chen; E R Giblett; W D Biggar; A A Ammann; C R Scott
Journal:  J Clin Invest       Date:  1977-09       Impact factor: 14.808

9.  Purine nucleoside phosphorylase, a possible histochemical marker for T-cells in man.

Authors:  M Borgers; H Verhaegen; M De Brabander; F Thoné; J van Reempts; G Geuens
Journal:  J Immunol Methods       Date:  1977       Impact factor: 2.303

10.  Rabbits possess conventional T lymphocytes.

Authors:  C Bell; H Wigzell
Journal:  Eur J Immunol       Date:  1977-10       Impact factor: 5.532
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