Literature DB >> 10384820

Experimental studies on lignans and cancer.

L U Thompson1.   

Abstract

Mammalian lignans are produced from plant precursors such as secoisolariciresinol diglycoside (SDG) and matairesinol via the action of bacteria in the human or animal colon. While precursors are found in many plant foods, flaxseed is the richest source of SDG and was therefore used as a model to determine the anti-cancer effects of lignans. This paper reviews the experimental studies in animals and humans demonstrating the anti-cancer effects of flaxseed and its SDG as well as other studies relevant to the clinical use of lignans, such as those on their food sources, bio-availability and safety.

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Year:  1998        PMID: 10384820     DOI: 10.1016/s0950-351x(98)80011-6

Source DB:  PubMed          Journal:  Baillieres Clin Endocrinol Metab        ISSN: 0950-351X


  14 in total

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Authors:  O Kayser; A F Kiderlen; S L Croft
Journal:  Parasitol Res       Date:  2003-02-20       Impact factor: 2.289

2.  Dietary phytoestrogen intake is associated with reduced colorectal cancer risk.

Authors:  Michelle Cotterchio; Beatrice A Boucher; Michael Manno; Steven Gallinger; Allan Okey; Patricia Harper
Journal:  J Nutr       Date:  2006-12       Impact factor: 4.798

3.  Intestinal bacterial communities that produce active estrogen-like compounds enterodiol and enterolactone in humans.

Authors:  Thomas Clavel; Gemma Henderson; Carl-Alfred Alpert; Catherine Philippe; Lionel Rigottier-Gois; Joël Doré; Michael Blaut
Journal:  Appl Environ Microbiol       Date:  2005-10       Impact factor: 4.792

Review 4.  Dietary factors modifying breast cancer risk and relation to time of intake.

Authors:  Airo Tsubura; Norihisa Uehara; Yasuhiko Kiyozuka; Nobuaki Shikata
Journal:  J Mammary Gland Biol Neoplasia       Date:  2005-01       Impact factor: 2.673

5.  Dietary walnuts inhibit colorectal cancer growth in mice by suppressing angiogenesis.

Authors:  Jutta M Nagel; Mary Brinkoetter; Faidon Magkos; Xiaowen Liu; John P Chamberland; Sunali Shah; Jinrong Zhou; George Blackburn; Christos S Mantzoros
Journal:  Nutrition       Date:  2011-07-27       Impact factor: 4.008

6.  No effect on adenoma formation in Min mice after moderate amount of flaxseed.

Authors:  S Oikarinen; S-M Heinonen; T Nurmi; H Adlercreutz; M Mutanen
Journal:  Eur J Nutr       Date:  2004-07-27       Impact factor: 5.614

7.  Can rye intake decrease risk of human breast cancer?

Authors:  Herman Adlercreutz
Journal:  Food Nutr Res       Date:  2010-11-10       Impact factor: 3.894

8.  (-) Arctigenin and (+) pinoresinol are antagonists of the human thyroid hormone receptor β.

Authors:  Ifedayo Victor Ogungbe; Rebecca A Crouch; Teresa Demeritte
Journal:  J Chem Inf Model       Date:  2014-11-13       Impact factor: 4.956

9.  Cancer killers in the human gut microbiota: diverse phylogeny and broad spectra.

Authors:  Yu-Jie Zhou; Dan-Dan Zhao; Huidi Liu; Hao-Ting Chen; Jia-Jing Li; Xiao-Qin Mu; Zheng Liu; Xia Li; Le Tang; Zhan-Yi Zhao; Ji-Heng Wu; Yu-Xuan Cai; Ya-Zhuo Huang; Peng-Ge Wang; Yi-Yue Jia; Pei-Qiang Liang; Xue Peng; Si-Yu Chen; Zhi-Lin Yue; Xin-Yuan Yuan; Tammy Lu; Bing-Qing Yao; Yong-Guo Li; Gui-Rong Liu; Shu-Lin Liu
Journal:  Oncotarget       Date:  2017-07-25

10.  Overcoming challenges in designing and implementing a phase II randomized controlled trial using a presurgical model to test a dietary intervention in prostate cancer.

Authors:  Wendy Demark-Wahnefried; Stephen L George; Boyd R Switzer; Denise C Snyder; John F Madden; Thomas J Polascik; Mack T Ruffin; Robin T Vollmer
Journal:  Clin Trials       Date:  2008       Impact factor: 2.486

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