| Literature DB >> 10382946 |
D Makower1, U Malik, Y Novik, P H Wiernik.
Abstract
Theophylline, a methylxanthine commonly used as a treatment for asthma, has been shown to induce apoptosis in chronic lymphocytic leukemia (CLL) cells both in vitro and in vivo. We have treated three advanced CLL patients with theophylline, and seen responses in two. The clinical courses of the responders are presented, and the literature concerning theophylline as therapy for CLL is reviewed.Entities:
Mesh：
Substances：
Year: 1999 PMID： 10382946 DOI： 10.1007/bf02787362
Source DB: PubMed Journal: Med Oncol ISSN： 1357-0560 Impact factor: 3.064