Literature DB >> 10379052

T-cell function in newborn mice and humans.

B Adkins1.   

Abstract

Neonates mount poor immune responses, and it has been assumed that neonatal T cells differ qualitatively from adult T cells. Here, Becky Adkins discusses this issue in the light of recent data indicating that T cells in neonates are developmentally mature in their capacity to mount protective Th1-type and cytotoxic T lymphocyte responses.

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Year:  1999        PMID： 10379052     DOI： 10.1016/s0167-5699(99)01473-5

Source DB:  PubMed          Journal:  Immunol Today        ISSN： 0167-5699


  71 in total

Review 1.  Type 1 and type 2 immune responses in children: their relevance in juvenile arthritis.

Authors:  L R Wedderburn; P Woo
Journal:  Springer Semin Immunopathol       Date:  1999

2.  Neonatal dendritic cells are intrinsically biased against Th-1 immune responses.

Authors:  C L Langrish; J C Buddle; A J Thrasher; D Goldblatt
Journal:  Clin Exp Immunol       Date:  2002-04       Impact factor: 4.330

3.  Selective enhancement of systemic Th1 immunity in immunologically immature rats with an orally administered bacterial extract.

Authors:  L M Bowman; P G Holt
Journal:  Infect Immun       Date:  2001-06       Impact factor: 3.441

4.  Neonates mount robust and protective adult-like CD8(+)-T-cell responses to DNA vaccines.

Authors:  Jie Zhang; Nicole Silvestri; J Lindsay Whitton; Daniel E Hassett
Journal:  J Virol       Date:  2002-12       Impact factor: 5.103

5.  Toxin levels in serum correlate with the development of staphylococcal scalded skin syndrome in a murine model.

Authors:  L R Plano; B Adkins; M Woischnik; R Ewing; C M Collins
Journal:  Infect Immun       Date:  2001-08       Impact factor: 3.441

6.  Constant IFNgamma mRNA to protein ratios in cord and adult blood T cells suggests regulation of IFNgamma expression in cord blood T cells occurs at the transcriptional level.

Authors:  A Kumar Gupta; C Rusterholz; W Holzgreve; S Hahn
Journal:  Clin Exp Immunol       Date:  2005-05       Impact factor: 4.330

7.  Induction of long-term protective antiviral endogenous immune response by short neutralizing monoclonal antibody treatment.

Authors:  Laurent Gros; Hanna Dreja; Anne Laure Fiser; Marc Plays; Mireia Pelegrin; Marc Piechaczyk
Journal:  J Virol       Date:  2005-05       Impact factor: 5.103

8.  Age, gender and litter-related variation in T-lymphocyte cytokine production in young pigs.

Authors:  Johanna de Groot; Leo Kruijt; Jan Willem Scholten; Wim J A Boersma; Willem G Buist; Bas Engel; Cornelis G van Reenen
Journal:  Immunology       Date:  2005-08       Impact factor: 7.397

9.  Responsiveness to respiratory syncytial virus in neonates is mediated through thymic stromal lymphopoietin and OX40 ligand.

Authors:  Junyan Han; Azzeddine Dakhama; Yi Jia; Meiqin Wang; Wanjiang Zeng; Katsuyuki Takeda; Yoshiki Shiraishi; Masakazu Okamoto; Steven F Ziegler; Erwin W Gelfand
Journal:  J Allergy Clin Immunol       Date:  2012-10-01       Impact factor: 10.793

10.  Immunoglobulin G subisotype responses of pneumonic and healthy, exposed foals and adult horses to Rhodococcus equi virulence-associated proteins.

Authors:  Kathleen E Hooper-McGrevy; Bruce N Wilkie; John F Prescott
Journal:  Clin Diagn Lab Immunol       Date:  2003-05
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