| Literature DB >> 10379048 |
Abstract
The relationship between acquired specific resistance and delayed-type hypersensitivity (DTH) in immunity to tuberculosis has long been a topic of debate. Here, Ian Orme and Andrea Cooper propose that the events are separate mechanisms; protection is cytokine driven and initially controls the infection, whereas DTH is primarily chemokine driven and functions to wall off the infection and prevent further dissemination.Entities:
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Year: 1999 PMID: 10379048 DOI: 10.1016/s0167-5699(98)01438-8
Source DB: PubMed Journal: Immunol Today ISSN: 0167-5699