| Literature DB >> 10377896 |
Abstract
The use of instrumental biosensors in basic research to measure biomolecular interactions in real time is increasing exponentially. Applications include protein-protein, protein-peptide, DNA-protein, DNA-DNA, and lipid-protein interactions. Such techniques have been applied to, for example, antibody-antigen, receptor-ligand, signal transduction, and nuclear receptor studies. This review outlines the principles of two of the most commonly used instruments and highlights specific operating parameters that will assist in optimising experimental design, data generation, and analysis.Entities:
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Year: 1999 PMID: 10377896 DOI: 10.1002/(SICI)1521-1878(199904)21:4<339::AID-BIES11>3.0.CO;2-C
Source DB: PubMed Journal: Bioessays ISSN: 0265-9247 Impact factor: 4.345