Literature DB >> 10377239

A conserved RGD (Arg-Gly-Asp) motif in the transferrin receptor is required for binding to transferrin.

V Dubljevic1, A Sali, J W Goding.   

Abstract

The transferrin receptor contains a highly conserved Arg-Gly-Asp (RGD) sequence in the C-terminal region where transferrin is thought to bind. RGD sequences are commonly involved in cell adhesion. This sequence is crucial for transferrin binding, suggesting possible evolutionary links between molecules mediating iron uptake and cell adhesion.

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Year:  1999        PMID： 10377239      PMCID： PMC1220324     

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  24 in total

1.  Exon/intron structure of the human transferrin receptor gene.

Authors:  P Evans; J Kemp
Journal:  Gene       Date:  1997-10-15       Impact factor: 3.688

2.  The hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand binding.

Authors:  J N Feder; D M Penny; A Irrinki; V K Lee; J A Lebrón; N Watson; Z Tsuchihashi; E Sigal; P J Bjorkman; R C Schatzman
Journal:  Proc Natl Acad Sci U S A       Date:  1998-02-17       Impact factor: 11.205

3.  Molecular structure of serum transferrin at 3.3-A resolution.

Authors:  S Bailey; R W Evans; R C Garratt; B Gorinsky; S Hasnain; C Horsburgh; H Jhoti; P F Lindley; A Mydin; R Sarra
Journal:  Biochemistry       Date:  1988-07-26       Impact factor: 3.162

4.  The human transferrin receptor gene: genomic organization, and the complete primary structure of the receptor deduced from a cDNA sequence.

Authors:  A McClelland; L C Kühn; F H Ruddle
Journal:  Cell       Date:  1984-12       Impact factor: 41.582

5.  Gene transfer, expression, and molecular cloning of the human transferrin receptor gene.

Authors:  L C Kühn; A McClelland; F H Ruddle
Journal:  Cell       Date:  1984-05       Impact factor: 41.582

6.  Binding of apotransferrin to K562 cells: explanation of the transferrin cycle.

Authors:  R D Klausner; G Ashwell; J van Renswoude; J B Harford; K R Bridges
Journal:  Proc Natl Acad Sci U S A       Date:  1983-04       Impact factor: 11.205

7.  pH and the recycling of transferrin during receptor-mediated endocytosis.

Authors:  A Dautry-Varsat; A Ciechanover; H F Lodish
Journal:  Proc Natl Acad Sci U S A       Date:  1983-04       Impact factor: 11.205

8.  The receptor for transferrin on murine myeloma cells: one-step purification based on its physiology, and partial amino acid sequence.

Authors:  I R van Driel; P A Stearne; B Grego; R J Simpson; J W Goding
Journal:  J Immunol       Date:  1984-12       Impact factor: 5.422

9.  Primary structure of human transferrin receptor deduced from the mRNA sequence.

Authors:  C Schneider; M J Owen; D Banville; J G Williams
Journal:  Nature       Date:  1984 Oct 18-24       Impact factor: 49.962

10.  Delivery of iron to human cells by bovine transferrin. Implications for the growth of human cells in vitro.

Authors:  S P Young; C Garner
Journal:  Biochem J       Date:  1990-01-15       Impact factor: 3.857
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  13 in total

1.  Temporal manipulation of transferrin-receptor-1-dependent iron uptake identifies a sensitive period in mouse hippocampal neurodevelopment.

Authors:  S J B Fretham; E S Carlson; J Wobken; P V Tran; A Petryk; M K Georgieff
Journal:  Hippocampus       Date:  2012-02-27       Impact factor: 3.899

2.  Transferrin receptor 2: continued expression in mouse liver in the face of iron overload and in hereditary hemochromatosis.

Authors:  R E Fleming; M C Migas; C C Holden; A Waheed; R S Britton; S Tomatsu; B R Bacon; W S Sly
Journal:  Proc Natl Acad Sci U S A       Date:  2000-02-29       Impact factor: 11.205

3.  How the binding of human transferrin primes the transferrin receptor potentiating iron release at endosomal pH.

Authors:  Brian E Eckenroth; Ashley N Steere; N Dennis Chasteen; Stephen J Everse; Anne B Mason
Journal:  Proc Natl Acad Sci U S A       Date:  2011-07-25       Impact factor: 11.205

4.  Molecular evolution of the transferrin receptor/glutamate carboxypeptidase II family.

Authors:  Lisa Ann Lambert; Stacey L Mitchell
Journal:  J Mol Evol       Date:  2006-12-09       Impact factor: 2.395

5.  Computational structure models of apo and diferric transferrin-transferrin receptor complexes.

Authors:  Tetsuya Sakajiri; Takaki Yamamura; Takeshi Kikuchi; Hirofumi Yajima
Journal:  Protein J       Date:  2009-12       Impact factor: 2.371

6.  Characterization of the interaction between diferric transferrin and transferrin receptor 2 by functional assays and atomic force microscopy.

Authors:  Katsuya Ikuta; Alexandre Yersin; Atsushi Ikai; Philip Aisen; Yutaka Kohgo
Journal:  J Mol Biol       Date:  2010-01-22       Impact factor: 5.469

7.  Mouse transferrin receptor 1 is the cell entry receptor for mouse mammary tumor virus.

Authors:  Susan R Ross; Jason J Schofield; Christine J Farr; Maja Bucan
Journal:  Proc Natl Acad Sci U S A       Date:  2002-09-06       Impact factor: 11.205

8.  Mechanism for multiple ligand recognition by the human transferrin receptor.

Authors:  Anthony M Giannetti; Peter M Snow; Olga Zak; Pamela J Björkman
Journal:  PLoS Biol       Date:  2003-12-22       Impact factor: 8.029

Review 9.  Intracellular iron transport and storage: from molecular mechanisms to health implications.

Authors:  Elizabeth L MacKenzie; Kenta Iwasaki; Yoshiaki Tsuji
Journal:  Antioxid Redox Signal       Date:  2008-06       Impact factor: 8.401

10.  Ferristatin II promotes degradation of transferrin receptor-1 in vitro and in vivo.

Authors:  Shaina L Byrne; Peter D Buckett; Jonghan Kim; Flora Luo; Jack Sanford; Juxing Chen; Caroline Enns; Marianne Wessling-Resnick
Journal:  PLoS One       Date:  2013-07-23       Impact factor: 3.240
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