Literature DB >> 10377158

Human monocytic U937 cells kill Salmonella in vitro by NO-independent mechanisms.

P Ekman1, M Saarinen, Q He, M Virtala, M Salmi, K Granfors.   

Abstract

Nitric oxide (NO) has a central role in host defense against intracellular microbes. HLA-B27 has been shown to directly modulate host-microbe interaction in vitro, leading to the impaired elimination of Salmonella in human monocytic U937 cells. Here, we studied whether impaired elimination of Salmonella would result from differences in NO production between HLA-B27- and HLA-A2-transfected U937 cells. Both human monocytic transfectants produced NO equally well and killed Salmonella via NO-independent mechanisms.

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Year:  1999        PMID： 10377158      PMCID： PMC116563     

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  26 in total

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Authors:  C F Nathan; J B Hibbs
Journal:  Curr Opin Immunol       Date:  1991-02       Impact factor: 7.486

Review 2.  The L-arginine-nitric oxide pathway.

Authors:  S Moncada; A Higgs
Journal:  N Engl J Med       Date:  1993-12-30       Impact factor: 91.245

Review 3.  Human monocytes/macrophages: NO or no NO?

Authors:  M Denis
Journal:  J Leukoc Biol       Date:  1994-05       Impact factor: 4.962

4.  The killing of Leishmania major by human macrophages is mediated by nitric oxide induced after ligation of the Fc epsilon RII/CD23 surface antigen.

Authors:  I Vouldoukis; V Riveros-Moreno; B Dugas; F Ouaaz; P Bécherel; P Debré; S Moncada; M D Mossalayi
Journal:  Proc Natl Acad Sci U S A       Date:  1995-08-15       Impact factor: 11.205

5.  Human mononuclear phagocyte inducible nitric oxide synthase (iNOS): analysis of iNOS mRNA, iNOS protein, biopterin, and nitric oxide production by blood monocytes and peritoneal macrophages.

Authors:  J B Weinberg; M A Misukonis; P J Shami; S N Mason; D L Sauls; W A Dittman; E R Wood; G K Smith; B McDonald; K E Bachus
Journal:  Blood       Date:  1995-08-01       Impact factor: 22.113

6.  Activation of human macrophages for the killing of intracellular Trypanosoma cruzi by TNF-alpha and IFN-gamma through a nitric oxide-dependent mechanism.

Authors:  M A Muñoz-Fernández; M A Fernández; M Fresno
Journal:  Immunol Lett       Date:  1992-06       Impact factor: 3.685

Review 7.  Nitric oxide as a secretory product of mammalian cells.

Authors:  C Nathan
Journal:  FASEB J       Date:  1992-09       Impact factor: 5.191

8.  Tumor necrosis factor and granulocyte macrophage-colony stimulating factor stimulate human macrophages to restrict growth of virulent Mycobacterium avium and to kill avirulent M. avium: killing effector mechanism depends on the generation of reactive nitrogen intermediates.

Authors:  M Denis
Journal:  J Leukoc Biol       Date:  1991-04       Impact factor: 4.962

9.  Production of angiogenic activity by human monocytes requires an L-arginine/nitric oxide-synthase-dependent effector mechanism.

Authors:  S J Leibovich; P J Polverini; T W Fong; L A Harlow; A E Koch
Journal:  Proc Natl Acad Sci U S A       Date:  1994-05-10       Impact factor: 11.205

10.  Regulation of nitric oxide synthase activity in human immunodeficiency virus type 1 (HIV-1)-infected monocytes: implications for HIV-associated neurological disease.

Authors:  M I Bukrinsky; H S Nottet; H Schmidtmayerova; L Dubrovsky; C R Flanagan; M E Mullins; S A Lipton; H E Gendelman
Journal:  J Exp Med       Date:  1995-02-01       Impact factor: 14.307
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  8 in total

Review 1.  The role of infection in the pathogenesis of spondyloarthropathies with special reference to human leukocyte antigen-B27.

Authors:  Markus A Penttinen; Yi Liu; Kaisa Granfors
Journal:  Curr Rheumatol Rep       Date:  2002-12       Impact factor: 4.592

2.  Nitric oxide metabolites in gnotobiotic piglets orally infected with Salmonella enterica serovar typhimurium.

Authors:  I Trebichavský; Z Zídek; D Franková; M Zahradnícková; I Splíchal
Journal:  Folia Microbiol (Praha)       Date:  2001       Impact factor: 2.099

Review 3.  Analysis of nitric oxide-dependent antimicrobial actions in macrophages and mice.

Authors:  Andrés Vazquez-Torres; Tania Stevanin; Jessica Jones-Carson; Margaret Castor; Robert C Read; Ferric C Fang
Journal:  Methods Enzymol       Date:  2008       Impact factor: 1.600

4.  N(2)O(3) enhances the nitrosative potential of IFNgamma-primed macrophages in response to Salmonella.

Authors:  Bruce D McCollister; Jesse T Myers; Jessica Jones-Carson; Maroof Husain; Travis J Bourret; Andrés Vázquez-Torres
Journal:  Immunobiology       Date:  2007-12-03       Impact factor: 3.144

5.  Microarray analysis of response of Salmonella during infection of HLA-B27- transfected human macrophage-like U937 cells.

Authors:  Shichao Ge; Vittoria Danino; Qiushui He; Jay C D Hinton; Kaisa Granfors
Journal:  BMC Genomics       Date:  2010-07-30       Impact factor: 3.969

6.  HLA-B27 modulates intracellular growth of Salmonella pathogenicity island 2 mutants and production of cytokines in infected monocytic U937 cells.

Authors:  Shichao Ge; Qiushui He; Kaisa Granfors
Journal:  PLoS One       Date:  2012-03-28       Impact factor: 3.240

7.  Antimicrobial actions of the NADPH phagocyte oxidase and inducible nitric oxide synthase in experimental salmonellosis. I. Effects on microbial killing by activated peritoneal macrophages in vitro.

Authors:  A Vazquez-Torres; J Jones-Carson; P Mastroeni; H Ischiropoulos; F C Fang
Journal:  J Exp Med       Date:  2000-07-17       Impact factor: 14.307

8.  HLA-B27 Correlates with the Intracellular Elimination, Replication, and Trafficking of Salmonella Enteritidis Collected from Reactive Arthritis Patients.

Authors:  Yi Zhao; Honghu Tang; Chunyu Tan; Hua Zhao; Yi Liu
Journal:  Med Sci Monit       Date:  2017-11-14
  8 in total

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