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Literature DB >> 10377157

Isolation and characterization of a sigB deletion mutant of Staphylococcus aureus.

R O Nicholas¹, T Li, D McDevitt, A Marra, S Sucoloski, P L Demarsh, D R Gentry.

Abstract

The sigB gene of Staphylococcus aureus, coding for the alternate sigma factor B, has been deleted by allelic replacement mutagenesis. The mutant grew as well as the parent in vitro, although it was deficient in clumping factor, coagulase, and pigment. In two murine and one rat infection model the mutant showed no reduction in virulence.

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Year: 1999 PMID： 10377157 PMCID： PMC116562

Source DB: PubMed Journal: Infect Immun ISSN： 0019-9567 Impact factor: 3.441

21 in total

1. The alternative sigma factor sigmaB in Staphylococcus aureus: regulation of the sigB operon in response to growth phase and heat shock

Authors:
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2. General stress transcription factor sigmaB and sporulation transcription factor sigmaH each contribute to survival of Bacillus subtilis under extreme growth conditions.

Authors: T A Gaidenko; C W Price
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3. The molecular architecture of the sar locus in Staphylococcus aureus.

Authors: M G Bayer; J H Heinrichs; A L Cheung
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4. Phenotypic characterization and virulence of a sae- agr- mutant of Staphylococcus aureus.

Authors: A T Giraudo; H Rampone; A Calzolari; R Nagel
Journal: Can J Microbiol Date: 1996-02 Impact factor: 2.419

Review 5. Structure and function of bacterial sigma factors.

Authors: J D Helmann; M J Chamberlin
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6. Specific and general stress proteins in Bacillus subtilis--a two-deimensional protein electrophoresis study.

Authors: J Bernhardt; U Völker; A Völker; H Antelmann; R Schmid; H Mach; M Hecker
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7. Genetic studies of a secondary RNA polymerase sigma factor in Bacillus subtilis.

Authors: M Igo; M Lampe; C Ray; W Schafer; C P Moran; R Losick
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8. Alternative transcription factor sigmaSB of Staphylococcus aureus: characterization and role in transcription of the global regulatory locus sar.

Authors: R Deora; T Tseng; T K Misra
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9. Regulation of exoprotein expression in Staphylococcus aureus by a locus (sar) distinct from agr.

Authors: A L Cheung; J M Koomey; C A Butler; S J Projan; V A Fischetti
Journal: Proc Natl Acad Sci U S A Date: 1992-07-15 Impact factor: 11.205

10. Coagulase expression in Staphylococcus aureus is positively and negatively modulated by an agr-dependent mechanism.

Authors: C Lebeau; F Vandenesch; T Greenland; R P Novick; J Etienne
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