Literature DB >> 10375557

CTLA-4 and T cell activation.

M A Oosterwegel1, R J Greenwald, D A Mandelbrot, R B Lorsbach, A H Sharpe.   

Abstract

The past year has seen significant advances in our understanding of the role of cytotoxic T lymphocyte antigen 4 (CTLA-4) in regulating T cell activation and tolerance. Recent studies indicate that CTLA-4 not only counterbalances CD28 signals but also can inhibit T cell responses independently of CD28. Recent work has also revealed a role for CTLA-4 in regulating Th1/Th2 differentiation. Manipulation of CTLA-4 in animal models of autoimmunity has shown that CTLA-4 regulates both the initiation and the progression of autoimmune diseases.

Entities:  

Mesh：

Substances：

Year:  1999        PMID： 10375557     DOI： 10.1016/s0952-7915(99)80047-8

Source DB:  PubMed          Journal:  Curr Opin Immunol        ISSN： 0952-7915            Impact factor:   7.486


  29 in total

1.  B7-dependent T-cell costimulation in mice lacking CD28 and CTLA4.

Authors:  D A Mandelbrot; M A Oosterwegel; K Shimizu; A Yamada; G J Freeman; R N Mitchell; M H Sayegh; A H Sharpe
Journal:  J Clin Invest       Date:  2001-04       Impact factor: 14.808

2.  Signaling through CD28 and CTLA-4 controls two distinct forms of T cell anergy.

Authors:  A D Wells; M C Walsh; J A Bluestone; L A Turka
Journal:  J Clin Invest       Date:  2001-09       Impact factor: 14.808

Review 3.  T lymphocyte dependence of the antibody response to 'T lymphocyte independent type 2' antigens.

Authors:  A Jeurissen; J L Ceuppens; X Bossuyt
Journal:  Immunology       Date:  2004-01       Impact factor: 7.397

Review 4.  Tumour-associated antigens: considerations for their use in tumour immunotherapy.

Authors:  Adam J Linley; Murrium Ahmad; Robert C Rees
Journal:  Int J Hematol       Date:  2011-03-01       Impact factor: 2.490

5.  Inhibitory receptors CD85j, LAIR-1, and CD152 down-regulate immunoglobulin and cytokine production by human B lymphocytes.

Authors:  Andrea Merlo; Claudya Tenca; Franco Fais; Lorenzo Battini; Ermanno Ciccone; Carlo E Grossi; Daniele Saverino
Journal:  Clin Diagn Lab Immunol       Date:  2005-06

6.  IL-17 and IFN-γ expression in lymphocytes from patients with active tuberculosis correlates with the severity of the disease.

Authors:  Javier O Jurado; Virginia Pasquinelli; Ivana B Alvarez; Delfina Peña; Ana I Rovetta; Nancy L Tateosian; Horacio E Romeo; Rosa M Musella; Domingo Palmero; H Eduardo Chuluyán; Verónica E García
Journal:  J Leukoc Biol       Date:  2012-03-13       Impact factor: 4.962

7.  Associations between cytotoxic T lymphocyte-associated antigen-4 polymorphisms and serum tumor necrosis factor-α and interferon-γ levels in patients with chronic hepatitis B virus infection.

Authors:  Qunying Han; Shaoqiong Duan; Guoyu Zhang; Zhu Li; Na Li; Qianqian Zhu; Yi Lv; Jinghong Chen; Zhengwen Liu
Journal:  Inflamm Res       Date:  2011-08-17       Impact factor: 4.575

8.  Regulatory T-cell markers, indoleamine 2,3-dioxygenase, and virus levels in spleen and gut during progressive simian immunodeficiency virus infection.

Authors:  Adriano Boasso; Monica Vaccari; Anna Hryniewicz; Dietmar Fuchs; Janos Nacsa; Valentina Cecchinato; Jan Andersson; Genoveffa Franchini; Gene M Shearer; Claire Chougnet
Journal:  J Virol       Date:  2007-08-22       Impact factor: 5.103

9.  Mouse TIGIT inhibits NK-cell cytotoxicity upon interaction with PVR.

Authors:  Noa Stanietsky; Tihana Lenac Rovis; Ariella Glasner; Einat Seidel; Pinchas Tsukerman; Rachel Yamin; Jonatan Enk; Stipan Jonjic; Ofer Mandelboim
Journal:  Eur J Immunol       Date:  2013-07-04       Impact factor: 5.532

10.  Impaired proteasome function activates GATA3 in T cells and upregulates CTLA-4: relevance for Sézary syndrome.

Authors:  Heather M Gibson; Anjali Mishra; Derek V Chan; Timothy S Hake; Pierluigi Porcu; Henry K Wong
Journal:  J Invest Dermatol       Date:  2012-09-06       Impact factor: 8.551
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.