[On the determination of triamterene, hydroxythiamterene and hydroxytriamterene sulphate ester in biologica material by direct evaluation of thin-layer chromatograms (author's transl)].

The quantitative measurement of 2,4,7-triamino-6-phenylpteridine (triamterene), as well as its metabolites hydroxytriamterene and hydroxytriamterene sulphate ester, is described. Estimation of urine, plasma and faecal samples was achieved by a direct fluorometric method following separation on kieselgel plates. The procedure allows the simultaneous assay of the three substances on the plate without the need for previous chromatographic separation or derivatisation.