BACKGROUND: Warts often present a difficult treatment problem for clinicians because of the lack of specific antipapillomavirus agents. Plantar warts, in particular, represent a therapeutic challenge. METHODS: Twenty-five patients with plantar warts were treated with Nd:YAG hyperthermia and another 25 were treated with cryotherapy. Biopsies were taken before and after treatment in both groups and were examined for the presence of human papillomavirus deoxyribonucleic acid (HPV DNA) using in situ hybridization (ISH). RESULTS: HPV DNA was detected in 100% of untreated warts and in 96% of cryotreated warts, but was not detected in any of the hyperthermia-treated warts. CONCLUSIONS: HPV is more vulnerable to hyperthermia than to cryotherapy.
BACKGROUND: Warts often present a difficult treatment problem for clinicians because of the lack of specific antipapillomavirus agents. Plantar warts, in particular, represent a therapeutic challenge. METHODS: Twenty-five patients with plantar warts were treated with Nd:YAG hyperthermia and another 25 were treated with cryotherapy. Biopsies were taken before and after treatment in both groups and were examined for the presence of human papillomavirus deoxyribonucleic acid (HPV DNA) using in situ hybridization (ISH). RESULTS: HPV DNA was detected in 100% of untreated warts and in 96% of cryotreated warts, but was not detected in any of the hyperthermia-treated warts. CONCLUSIONS: HPV is more vulnerable to hyperthermia than to cryotherapy.
Authors: Abd El-Shakor El-Mohamady; Ibrahim Mearag; Mohamed El-Khalawany; Ahmed Elshahed; Hisham Shokeir; Anas Mahmoud Journal: Lasers Med Sci Date: 2013-11-12 Impact factor: 3.161
Authors: Sara García-Oreja; Francisco Javier Álvaro-Afonso; Aroa Tardáguila-García; Mateo López-Moral; Marta García-Madrid; José Luis Lázaro-Martínez Journal: Dermatol Ther Date: 2022-04-06 Impact factor: 3.858
Authors: Luigi Bennardo; Gaia Fasano; Federica Tamburi; Elena Zappia; Francesco Rizzuto; Steven Paul Nisticò; Giovanni Cannarozzo Journal: Medicina (Kaunas) Date: 2022-01-12 Impact factor: 2.430