Literature DB >> 1036895

X-ray crystallographic and gas chromatographic--mass spectrometric studies on norpropoxyphene.

G Norheim, E Bye.   

Abstract

The crystal structure of norpropoxyphene maleate is presented. The conformation is discussed in relation to similar compounds. A gas chromatographic--mass spectrometric investigation indicates that earlier proposed metabolites may be formed during the gas chromatographic separation.

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Year:  1976        PMID： 1036895     DOI： 10.1007/BF00351967

Source DB:  PubMed          Journal:  Arch Toxicol        ISSN： 0340-5761            Impact factor:   5.153


  9 in total

1.  Crystal structures of synthetic analgetics. IV. Dextropropoxyphene.

Authors:  E Bye
Journal:  Acta Chem Scand B       Date:  1975

2.  Analgesics and their antagonists: some steric and chemical considerations. I. The dissociation constants of some tertiary amines and synthetic analgesics, the conformations of methadone-type compounds.

Authors:  A H BECKETT
Journal:  J Pharm Pharmacol       Date:  1956-11       Impact factor: 3.765

3.  Identification and quantitative determination of some metabolites of methadone, isomethadone and normethadone.

Authors:  A H Beckett; M Mitchard; A A Shihab
Journal:  J Pharm Pharmacol       Date:  1971-05       Impact factor: 3.765

4.  The biotransformation of methadone in man: synthesis and identification of a major metabolite.

Authors:  A H Beckett; J F Taylor; A F Casy; M M Hassan
Journal:  J Pharm Pharmacol       Date:  1968-10       Impact factor: 3.765

5.  A GC-MS reference data system for the identification of drugs of abuse.

Authors:  B S Finkle; D M Taylor; E J Bonelli
Journal:  J Chromatogr Sci       Date:  1972-05       Impact factor: 1.618

6.  Identification of the drug Darvon and its metabolites in the urine of a comatose patient using a gas chromatograph-mass spectrometer-computer system.

Authors:  J R Althaus; K Biemann; J Biller; P F Donaghue; D A Evans; H J Förster; H S Hertz; C E Hignite; R C Murphy; G Preti; V Reinhold
Journal:  Experientia       Date:  1970

7.  Synthesis and identification of metabolites resulting from the biotransformation of DL-methadone in man and in the rat.

Authors:  A Pohland; H E Boaz; H R Sullivan
Journal:  J Med Chem       Date:  1971-03       Impact factor: 7.446

8.  Crystal structures of synthetic analgetics. V. Dextromoramide.

Authors:  E Bye
Journal:  Acta Chem Scand B       Date:  1976

9.  Quantitation of propoxyphene and its major metabolites in heroin addict plasma after large dose administration of propoxyphene napsylate.

Authors:  J F Nash; I F Bennett; R J Bopp; M K Brunson; H R Sullivan
Journal:  J Pharm Sci       Date:  1975-03       Impact factor: 3.534
  9 in total
  1 in total

1.  Determination of dextropropoxyphene and norpropoxyphene in autopsy material by gas chromatography.

Authors:  G Norheim
Journal:  Arch Toxicol       Date:  1976-10-28       Impact factor: 5.153
  1 in total

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