BACKGROUND: Abdominal hernia repair with implantation of synthetic meshes using the sublay technique has resulted in low recurrence rates and high patient satisfaction. AIM: The purpose of this experimental animal study was to investigate whether mesh fixation is necessary in abdominal hernia repair using a polypropylene mesh in the sublay technique. METHODS: Forty-five rats were divided into three groups after creating an abdominal wall defect (CG control group, no mesh implantation; NoFixG mesh implantation without fixation group; SG mesh with suture fixation group) with 15 animals in each group. End-points were clinical herniation pressure, hydroxyproline (HP) concentration, mesh shape and number of fibroblasts/collagen fibres of the anchor zone 7, 14 and 90 days after implantation. RESULTS: Herniation pressure, HP content and number of fibroblasts were similar between NoFixG and SG, although significantly higher in these groups than in the CG (P<0.05). Both mesh groups had significantly higher counts of fibroblasts and collagen fibres than the CG. Mesh shrinking occurred in both groups but was less in the SG. CONCLUSION: Mesh fixation was not mandatory in abdominal hernia repair using this animal model.
BACKGROUND:Abdominal hernia repair with implantation of synthetic meshes using the sublay technique has resulted in low recurrence rates and high patient satisfaction. AIM: The purpose of this experimental animal study was to investigate whether mesh fixation is necessary in abdominal hernia repair using a polypropylene mesh in the sublay technique. METHODS: Forty-five rats were divided into three groups after creating an abdominal wall defect (CG control group, no mesh implantation; NoFixG mesh implantation without fixation group; SG mesh with suture fixation group) with 15 animals in each group. End-points were clinical herniation pressure, hydroxyproline (HP) concentration, mesh shape and number of fibroblasts/collagen fibres of the anchor zone 7, 14 and 90 days after implantation. RESULTS: Herniation pressure, HP content and number of fibroblasts were similar between NoFixG and SG, although significantly higher in these groups than in the CG (P<0.05). Both mesh groups had significantly higher counts of fibroblasts and collagen fibres than the CG. Mesh shrinking occurred in both groups but was less in the SG. CONCLUSION: Mesh fixation was not mandatory in abdominal hernia repair using this animal model.
Authors: Amit Kaul; Susan Hutfless; Hamilton Le; Senan A Hamed; Kevin Tymitz; Hien Nguyen; Michael R Marohn Journal: Surg Endosc Date: 2012-02-21 Impact factor: 4.584
Authors: Bernhard J Leibl; Barbara Kraft; Jens Daniel Redecke; Claus Georg Schmedt; Martin Ulrich; Klaus Kraft; Reinhard Bittner Journal: World J Surg Date: 2002-09-26 Impact factor: 3.352
Authors: Eric D Jenkins; Lora Melman; Salil Desai; Shaun R Brown; Margaret M Frisella; Corey R Deeken; Brent D Matthews Journal: Surg Endosc Date: 2010-07-22 Impact factor: 4.584