| Literature DB >> 1036689 |
A R Poole, R M Hembry, J T Dingle, I Pinder, E F Ring, J Cosh.
Abstract
The proteinase cathepsin D which degrades proteoglycan was never demonstrated in extracellular sites in tissues from patients with traumatized meniscoid cartilage, either before or after culture with an antiserum to human cathepsin D. In contrast, in synovia (but not usually cartilage) from the knees of 6 of 11 rheumatoid patients, extracellular cathepsin D was commonly detected by culturing tissues with an antiserum to this enzyme.Entities:
Mesh：
Substances：
Year: 1976 PMID： 1036689 DOI： 10.1002/art.1780190610
Source DB: PubMed Journal: Arthritis Rheum ISSN： 0004-3591