Literature DB >> 10366862

Molecular mechanisms of yeast longevity.

S M Jazwinski1.   

Abstract

The genetic analysis of yeast longevity has illuminated the underlying molecular mechanisms of aging that invoke the importance of metabolic regulation, genetic stability and stress resistance in determination of life span. The RAS genes have emerged as important modulators of life-maintenance processes and of life span itself.

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Year:  1999        PMID: 10366862     DOI: 10.1016/s0966-842x(99)01509-7

Source DB:  PubMed          Journal:  Trends Microbiol        ISSN: 0966-842X            Impact factor:   17.079


  13 in total

1.  The transcriptome of prematurely aging yeast cells is similar to that of telomerase-deficient cells.

Authors:  Isabelle Lesur; Judith L Campbell
Journal:  Mol Biol Cell       Date:  2004-01-12       Impact factor: 4.138

Review 2.  Successful ageing: from cell to self.

Authors:  S J Lupien; N Wan
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2004-09-29       Impact factor: 6.237

Review 3.  The retrograde response: a conserved compensatory reaction to damage from within and from without.

Authors:  S Michal Jazwinski
Journal:  Prog Mol Biol Transl Sci       Date:  2014       Impact factor: 3.622

4.  Identification of the Target of the Retrograde Response that Mediates Replicative Lifespan Extension in Saccharomyces cerevisiae.

Authors:  James C Jiang; Stefan W Stumpferl; Anurag Tiwari; Qian Qin; José F Rodriguez-Quiñones; S Michal Jazwinski
Journal:  Genetics       Date:  2016-07-29       Impact factor: 4.562

5.  The short life span of Saccharomyces cerevisiae sgs1 and srs2 mutants is a composite of normal aging processes and mitotic arrest due to defective recombination.

Authors:  M McVey; M Kaeberlein; H A Tissenbaum; L Guarente
Journal:  Genetics       Date:  2001-04       Impact factor: 4.562

Review 6.  Programmed death in bacteria.

Authors:  K Lewis
Journal:  Microbiol Mol Biol Rev       Date:  2000-09       Impact factor: 11.056

Review 7.  Mitochondria to nucleus signaling and the role of ceramide in its integration into the suite of cell quality control processes during aging.

Authors:  S M Jazwinski
Journal:  Ageing Res Rev       Date:  2014-12-31       Impact factor: 10.895

8.  C26-CoA-dependent ceramide synthesis of Saccharomyces cerevisiae is operated by Lag1p and Lac1p.

Authors:  I Guillas; P A Kirchman; R Chuard; M Pfefferli; J C Jiang; S M Jazwinski; A Conzelmann
Journal:  EMBO J       Date:  2001-06-01       Impact factor: 11.598

9.  The oncogenic RAS2(val19) mutation locks respiration, independently of PKA, in a mode prone to generate ROS.

Authors:  Lydie Hlavatá; Hugo Aguilaniu; Alena Pichová; Thomas Nyström
Journal:  EMBO J       Date:  2003-07-01       Impact factor: 11.598

10.  Patterns of metabolic activity during aging of the wild type and longevity mutants of Caenorhabditis elegans.

Authors:  B P Braeckman; K Houthoofd; J R Vanfleteren
Journal:  J Am Aging Assoc       Date:  2000-04
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