Literature DB >> 10364673

Maternal fertility is not affected by fetal surgery.

J A Farrell1, C T Albanese, R W Jennings, S J Kilpatrick, B J Bratton, M R Harrison.   

Abstract

The purpose of this report is to assess the impact of fetal surgery on future maternal fertility, subsequent pregnancy outcome, and the incidence of pregnancy complications. Retrospective data were collected on 70 mothers who underwent fetal surgery between April 1981 and June 1996. Indications for open hysterotomy fetal surgery included congenital diaphragmatic hernia (n = 44), congenital cystic adenomatoid malformation of the lung (n = 11), urinary obstruction (n = 9), sacrococcygeal teratoma (n = 4), heart block (n = 1), and acardiac-acephalic twin reduction (n = 1). The following data were obtained: number of pregnancy attempts, number of successful pregnancies, pregnancy outcome including obstetrical and neonatal complications, and infertility after fetal surgery. There were 45 respondents, of whom 35 attempted subsequent pregnancies. Thirty-two were successful, resulting in 31 livebirths. Two women had a strong prefetal surgery history of infertility, 1 has only attempted to conceive for 3 months. We report this experience because the effect of open fetal surgery on futrue fertility is such an important question for our patients and referring physicians. This analysis suggests that hysterotomy and open fetal surgery has a negligible impact on maternal fertility.

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Mesh:

Year:  1999        PMID: 10364673     DOI: 10.1159/000020918

Source DB:  PubMed          Journal:  Fetal Diagn Ther        ISSN: 1015-3837            Impact factor:   2.587


  6 in total

1.  Fetal surgery.

Authors:  Diana Farmer
Journal:  BMJ       Date:  2003-03-01

Review 2.  Fetal surgery for myelomeningocele.

Authors:  Payam Saadai; Diana L Farmer
Journal:  Clin Perinatol       Date:  2012-05-15       Impact factor: 3.430

Review 3.  Maternal-fetal surgery: the fallacy of abstraction and the problem of equipoise.

Authors:  A D Lyerly; M B Mahowald
Journal:  Health Care Anal       Date:  2001

4.  A randomized trial of prenatal versus postnatal repair of myelomeningocele.

Authors:  N Scott Adzick; Elizabeth A Thom; Catherine Y Spong; John W Brock; Pamela K Burrows; Mark P Johnson; Lori J Howell; Jody A Farrell; Mary E Dabrowiak; Leslie N Sutton; Nalin Gupta; Noel B Tulipan; Mary E D'Alton; Diana L Farmer
Journal:  N Engl J Med       Date:  2011-02-09       Impact factor: 91.245

5.  Anesthesia for in utero repair of myelomeningocele.

Authors:  Marla Ferschl; Robert Ball; Hanmin Lee; Mark D Rollins
Journal:  Anesthesiology       Date:  2013-05       Impact factor: 7.892

6.  Maternal complications following open and fetoscopic fetal surgery: A systematic review and meta-analysis.

Authors:  Adalina Sacco; Lennart Van der Veeken; Emma Bagshaw; Catherine Ferguson; Tim Van Mieghem; Anna L David; Jan Deprest
Journal:  Prenat Diagn       Date:  2019-02-27       Impact factor: 3.050

  6 in total

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