Literature DB >> 10364510

Function and dysfunction of the presenilins.

S S Sisodia1, S H Kim, G Thinakaran.   

Abstract

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Year:  1999        PMID： 10364510      PMCID： PMC1378068          DOI： 10.1086/302475

Source DB:  PubMed          Journal:  Am J Hum Genet        ISSN： 0002-9297            Impact factor:   11.025


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  42 in total

Review 1.  Microglia and the immune pathology of Alzheimer disease.

Authors:  D Giulian
Journal:  Am J Hum Genet       Date:  1999-07       Impact factor: 11.025

2.  Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity.

Authors:  M S Wolfe; W Xia; B L Ostaszewski; T S Diehl; W T Kimberly; D J Selkoe
Journal:  Nature       Date:  1999-04-08       Impact factor: 49.962

3.  Neurogenic phenotypes and altered Notch processing in Drosophila Presenilin mutants.

Authors:  Y Ye; N Lukinova; M E Fortini
Journal:  Nature       Date:  1999-04-08       Impact factor: 49.962

4.  Presenilin is required for activity and nuclear access of Notch in Drosophila.

Authors:  G Struhl; I Greenwald
Journal:  Nature       Date:  1999-04-08       Impact factor: 49.962

5.  A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain.

Authors:  B De Strooper; W Annaert; P Cupers; P Saftig; K Craessaerts; J S Mumm; E H Schroeter; V Schrijvers; M S Wolfe; W J Ray; A Goate; R Kopan
Journal:  Nature       Date:  1999-04-08       Impact factor: 49.962

6.  Evidence that intramolecular associations between presenilin domains are obligatory for endoproteolytic processing.

Authors:  C A Saura; T Tomita; F Davenport; C L Harris; T Iwatsubo; G Thinakaran
Journal:  J Biol Chem       Date:  1999-05-14       Impact factor: 5.157

7.  Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene.

Authors:  E I Rogaev; R Sherrington; E A Rogaeva; G Levesque; M Ikeda; Y Liang; H Chi; C Lin; K Holman; T Tsuda
Journal:  Nature       Date:  1995-08-31       Impact factor: 49.962

8.  Genetic linkage evidence for a familial Alzheimer's disease locus on chromosome 14.

Authors:  G D Schellenberg; T D Bird; E M Wijsman; H T Orr; L Anderson; E Nemens; J A White; L Bonnycastle; J L Weber; M E Alonso
Journal:  Science       Date:  1992-10-23       Impact factor: 47.728

9.  Candidate gene for the chromosome 1 familial Alzheimer's disease locus.

Authors:  E Levy-Lahad; W Wasco; P Poorkaj; D M Romano; J Oshima; W H Pettingell; C E Yu; P D Jondro; S D Schmidt; K Wang
Journal:  Science       Date:  1995-08-18       Impact factor: 47.728

10.  A familial Alzheimer's disease locus on chromosome 1.

Authors:  E Levy-Lahad; E M Wijsman; E Nemens; L Anderson; K A Goddard; J L Weber; T D Bird; G D Schellenberg
Journal:  Science       Date:  1995-08-18       Impact factor: 47.728
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  19 in total

Review 1.  Microglia and the immune pathology of Alzheimer disease.

Authors:  D Giulian
Journal:  Am J Hum Genet       Date:  1999-07       Impact factor: 11.025

2.  Amyloid angiopathy and variability in amyloid beta deposition is determined by mutation position in presenilin-1-linked Alzheimer's disease.

Authors:  D M Mann; S M Pickering-Brown; A Takeuchi; T Iwatsubo
Journal:  Am J Pathol       Date:  2001-06       Impact factor: 4.307

3.  Presenilins regulate the cellular level of the tumor suppressor PTEN.

Authors:  Han Zhang; Runzhong Liu; Ruishan Wang; Shuigen Hong; Huaxi Xu; Yun-wu Zhang
Journal:  Neurobiol Aging       Date:  2007-01-12       Impact factor: 4.673

Review 4.  Potential treatment opportunities for Alzheimer's disease through inhibition of secretases and Abeta immunization.

Authors:  D Schenk; D Games; P Seubert
Journal:  J Mol Neurosci       Date:  2001-10       Impact factor: 3.444

Review 5.  The beta-secretase, BACE: a prime drug target for Alzheimer's disease.

Authors:  R Vassar
Journal:  J Mol Neurosci       Date:  2001-10       Impact factor: 3.444

6.  The presenilin loop region is essential for glycogen synthase kinase 3 β (GSK3β) mediated functions on motor proteins during axonal transport.

Authors:  Rupkatha Banerjee; Zoe Rudloff; Crystal Naylor; Michael C Yu; Shermali Gunawardena
Journal:  Hum Mol Genet       Date:  2018-09-01       Impact factor: 6.150

7.  Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation.

Authors:  Holly Oakley; Sarah L Cole; Sreemathi Logan; Erika Maus; Pei Shao; Jeffery Craft; Angela Guillozet-Bongaarts; Masuo Ohno; John Disterhoft; Linda Van Eldik; Robert Berry; Robert Vassar
Journal:  J Neurosci       Date:  2006-10-04       Impact factor: 6.167

Review 8.  Presenilins and APP in neuritic and synaptic plasticity: implications for the pathogenesis of Alzheimer's disease.

Authors:  Sic L Chan; Katsutoshi Furukawa; Mark P Mattson
Journal:  Neuromolecular Med       Date:  2002       Impact factor: 3.843

Review 9.  BACE1: the beta-secretase enzyme in Alzheimer's disease.

Authors:  Robert Vassar
Journal:  J Mol Neurosci       Date:  2004       Impact factor: 3.444

10.  The Basic Biology of BACE1: A Key Therapeutic Target for Alzheimer's Disease.

Authors:  S L Cole; R Vassar
Journal:  Curr Genomics       Date:  2007-12       Impact factor: 2.236
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