Literature DB >> 10364051

A pilot study of iron depletion as adjuvant therapy in chronic hepatitis C patients not responding to interferon.

D Guyader1, E Boucher, P André, C Even, J Cottereau, A Bianchi, P Gasser, M H Mendler, Y Deugnier, P Brissot.   

Abstract

The aim of this study was to assess the efficacy of iron depletion obtained by phlebotomy to enhance interferon response in 11 patients who had failed to respond to a standard 3-month interferon treatment. Despite a significant effect on serum aminotransferase levels, there was no effect on viremia, and iron depletion was unable to trigger interferon response.

Entities:  

Mesh：

Substances：

Year:  1999        PMID： 10364051     DOI： 10.1111/j.1572-0241.1999.01170.x

Source DB:  PubMed          Journal:  Am J Gastroenterol        ISSN： 0002-9270            Impact factor:   10.864


  7 in total

Review 1.  Treatment of chronic hepatitis C in nonresponders to interferon monotherapy.

Authors:  P Y Kwo
Journal:  Curr Gastroenterol Rep       Date:  2000-02

2.  Identification of treatment efficacy-related host factors in chronic hepatitis C by ProteinChip serum analysis.

Authors:  Naoki Fujita; Mamoru Nakanishi; Jun Mukai; Yuuji Naito; Takafumi Ichida; Masahiko Kaito; Toshikazu Yoshikawa; Yoshiyuki Takei
Journal:  Mol Med       Date:  2010-10-05       Impact factor: 6.354

Review 3.  The role of iron in the pathophysiology and treatment of chronic hepatitis C.

Authors:  Leslie Price; Kris V Kowdley
Journal:  Can J Gastroenterol       Date:  2009-12       Impact factor: 3.522

4.  Iron increases translation initiation directed by internal ribosome entry site of hepatitis C virus.

Authors:  Hana Cho; Hyung Chul Lee; Sung Key Jang; Yoon Ki Kim
Journal:  Virus Genes       Date:  2008-06-20       Impact factor: 2.332

5.  The effect of iron depletion on chronic hepatitis C virus infection.

Authors:  Massimo Franchini; Giovanni Targher; Franco Capra; Martina Montagnana; Giuseppe Lippi
Journal:  Hepatol Int       Date:  2008-05-08       Impact factor: 6.047

Review 6.  Iron overload and cofactors with special reference to alcohol, hepatitis C virus infection and steatosis/insulin resistance.

Authors:  Yutaka Kohgo; Katsuya Ikuta; Takaaki Ohtake; Yoshihiro Torimoto; Junji Kato
Journal:  World J Gastroenterol       Date:  2007-09-21       Impact factor: 5.742

Review 7.  HCV and oxidative stress in the liver.

Authors:  Alexander V Ivanov; Birke Bartosch; Olga A Smirnova; Maria G Isaguliants; Sergey N Kochetkov
Journal:  Viruses       Date:  2013-01-28       Impact factor: 5.048
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.